用于传染病诊断的新型检测技术  

Cutting-edge detection technologies for the diagnosis of infectious diseases

作　　者：高晓薇 宋浩 仇华吉[1] 罗玉子[1] GAO Xiaowei;SONG Hao;QIU Huaji;LUO Yuzi(State Key Laboratory for Animal Disease Control and Prevention,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150069,China)

机构地区：[1]中国农业科学院哈尔滨兽医研究所动物疫病防控全国重点实验室,黑龙江哈尔滨150069

出　　处：《中国兽医学报》2024年第6期1325-1335,共11页Chinese Journal of Veterinary Science

基　　金：黑龙江省自然科学基金资助项目(LH2023C052);国家自然科学基金联合基金资助项目(U20A2060)。

摘　　要：新发和再发传染病严重威胁着全球卫生安全,给世界各国的经济和生活带来了巨大影响,快速检测和鉴定对传染病的监测、预警与防控至关重要。近年来,随着新型材料和科学技术日新月异的发展,检测技术不断创新与应用,逐步向着自动化、高通量、即时诊断的方向发展。本文综述了包括CRISPR系统、微流控技术、纳米PCR等传染病诊断新技术的研究进展,分析了各种新型检测技术的优势和局限性及其应用,并对检测技术的未来发展方向提出展望,旨在为人类与动物疫病的监测提供建议。Currently,emerging and re-emerging infectious diseases pose a serious threat to global health security,and have a huge impact on the economies and daily lives of countries around the world.Rapid detection and identification are crucial for monitoring,early warning,and prevention and control of infectious diseases.In recent years,with the rapid development of new materials and scientific technology,detection techniques have continued to innovate and be applied,progressively advancing towards automation,high throughput and real-time diagnosis.This article summarizes the research progress of new infectious disease diagnosis technologies,including CRISPR system,microfluidics technology,and nanoscale PCR,analyzes the advantages and limitations of various new detection technologies and their applications,and proposes prospects for the future development of detection technologies,in the hope of providing recommendations for monitoring human and animal diseases.

关 键 词：新型检测技术 传染病 研究进展 

分 类 号：S852.65[农业科学—基础兽医学]