Technologies for investigating single-molecule chemical reactions  

作　　者：Chunyan Gao Qinghua Gao Cong Zhao Yani Huo Zhizhuo Zhang Jinlong Yang Chuancheng Jia Xuefeng Guo 

机构地区：[1]Centerof Single-Molecule Sciences,Instituteof Modern Optics,Frontiers Science Center for New Organic Matter,Tianjin Key Laboratory of Micro-Scale Optical Information Science and Technology,College of Electronic Information and Optical Engineering,Nankai University,Tianjin 300350,China [2]Hefei National Research Center for Physical Sciences at Microscale,University of Scienceand Technology of China,Hefei 230026,China [3]Beijing National Laboratory for Molecular Sciences,National Biomedical Imaging Center,College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China

出　　处：《National Science Review》2024年第8期316-346,共31页国家科学评论（英文版）

基　　金：supported by the National Key Research and Development Program of China (2021YFA1200102,2021YFA1200101 and 2022YFE0128700);the National Natural Science Foundation of China (22173050,22150013,21727806 and 21933001);the Natural Science Foundation of Beijing (2222009);the Beijing National Laboratory for Molecular Sciences (BNLMS-CXXM-202407).

摘　　要：Single molecules,the smallest independently stable units in the material world,serve as the fundamental building blocks of matter.Among different branches of single-molecule sciences,single-molecule chemical reactions,by revealing the behavior and properties of individual molecules at the molecular scale,are particularly attractive because they can advance the understanding of chemical reaction mechanisms and help to address key scientific problems in broad fields such as physics,chemistry,biology and materials science.This review provides a timely,comprehensive overview of single-molecule chemical reactions based on various technical platforms such as scanning probe microscopy,single-molecule junction,single-molecule nanostructure,single-molecule fluorescence detection and crossed molecular beam.We present multidimensional analyses of single-molecule chemical reactions,offering new perspectives for research in diferent areas,such as photocatalysis/electrocatalysis,organic reactions,surface reactions and biological reactions.Finally,we discuss the opportunities and challenges in this thriving field of single-molecule chemical reactions.

关 键 词：chemical reaction scanning probe microscopy single-molecule junction single-molecule fluorescence crossed molecular beam 

分 类 号：O62[理学—有机化学]