Research on the Nursing Effect of Glycolipids on Acne Skin  

作　　者：Wang Huiyu Zha Jiansheng Tong Li Yan Xiaodong Wang Jing 

机构地区：[1]Spec-Chem Industry Inc.,Ltd.,China [2]School of Chemistry and Materials Engineering,Jiangnan University,China

出　　处：《China Detergent & Cosmetics》2024年第3期33-40,共8页日用化学品科学（英文版）

摘　　要：Glycolipids are lipid compounds,which are a type of amphiphilic molecules containing glycosyl ligands.This experiment studied the efficacy of glycolipids on acne skin care from the aspects of antibacterial,anti-inflammatory,anti-allergic,oil-control,soothing and repair.Research results show that glycolipids have excellent antibacterial properties against P.acnes;when the dosage of glycolipids reaches 10μg/mL,the inhibition rate of glycolipids on lipid synthesis in SZ95 cells can reach 20%;glycolipids can induce LPS induction RAW264.7 cells have the inhibitory effect on the release of inflammatory factors IL-6 and NO;when the glycolipids concentration is 15 mg/mL,the inhibition rate of glycolipids on hyaluronidase reaches 45.8%;when the glycolipids concentration is 25μg/mL,the inhibition rate on calcium ion concentration reaches 45.3%;glycolipids have a significant promoting effect on wound healing.Furthermore,human efficacy evaluation shows that glycolipids products have comprehensive care effects on acne skin.This study will help further promote the application of glycolipids in cosmetic products,especially in skin care products for acne skin.

关 键 词：GLYCOLIPIDS acne skin oil-control ANTIBACTERIAL ANTI-INFLAMMATORY 

分 类 号：TQ658[化学工程—精细化工]