Evaluation of Anti-Wrinkle, Relieving Effect and Safety of A Group of Hexapeptide Compounds  

作　　者：Huang Jia He Xingxing Zhao Yue Ma Xiaoyu Lu Chaogang Li Xiang 

机构地区：[1]Shaanxi HuiKang Bio-Tech Co.,Ltd.,China

出　　处：《China Detergent & Cosmetics》2024年第3期56-61,共6页日用化学品科学（英文版）

摘　　要：The anti-wrinkle,relieving effect and safety of a group of hexapeptide compounds(HCs)were evaluated by in vitro antioxidant test,hyaluronidase inhibition test and human clinical test.The results showed that HCs possess+high overall antioxidant activity,and the scavenging activity of ABTS•radical and DPPH radical by 4 mg/mL HCs solution were(92.23±1.15)%and(90.24±1.25)%.The scavenging activity of PTIO radical by 80 mg/mL HCs solution was(80.29±2.41)%.The inhibition rate of 80 mg/mL HCs on hyaluronidase was(75.00±6.13)%.The test of clinical results showed that the HCs have good anti-wrinkle and relieving effect,and no case of grade 1 or above skin adverse reactions occurred,indicating that HCs have good safety.

关 键 词：hexapeptide compounds ANTI-WRINKLE relieving effect antioxidant activity SAFETY 

分 类 号：TQ658[化学工程—精细化工]