茶芎化学成分及药理活性研究进展  

Research Progress on Chemical Constituents and Pharmacological Activities of Ligusticum sinense Oliv.Cv.Chaxiong

作　　者：高博闻[1] 杨建波[2] 梁茹 田彩云[1] 陈婧 杨庆瑞 张国松 樊凌暄 王莹[2] GAO Bo-wen;YANG Jian-bo;LIANG Ru;TIAN Cai-yun;CHEN Jing;YANG Qing-rui;ZHANG Guo-song;FAN Ling-xuan;WANG Ying(Baotou Medical College,Baotou 014040,China;National Institutes for Food and Drug Control,Beijing 100050,China;School of Pharmacy,Jiangxi University of Chinese Medicine,Nanchang 330006,China)

机构地区：[1]包头医学院,内蒙古包头014040 [2]中国食品药品检定研究院,北京100050 [3]江西中医药大学药学院,江西南昌330006

出　　处：《中国现代中药》2024年第9期1596-1607,共12页Modern Chinese Medicine

基　　金：国家自然科学基金项目(82260771);江西省“科技+中医药”联合计划项目;江西省中医药标委会2023年第一批标准化项目(2023A20)。

摘　　要：茶芎Ligusticum sinense Oliv.Cv.Chaxiong为江西省特产中药材之一,主要含有苯酞类等化学成分,具有活血行气、祛风止痛等功效。同时,茶芎的有效成分在抗惊厥、抗癫痫、抗炎镇痛、保护心脑血管及改善学习记忆能力等方面具有较好的药理活性。通过查阅国内外文献,对近30年来报道的关于茶芎化学成分和药理活性方面的内容进行系统综述,为将来更好地开发和利用茶芎提供参考。Ligusticum sinense Oliv.Cv.Chaxiong is a specialty traditional Chinese medicinal material from Jiangxi province.It primarily contains phthalide compounds and other chemical constituents.L.sinense Oliv.Cv.Chaxiong has clinical effects in promoting blood circulation and qi flow,expelling wind,and relieving pain.Additionally,the effective ingredients in L.sinense Oliv.Cv.Chaxiong have shown significant pharmacological activities,including anticonvulsant,antiepileptic,anti-inflammatory,analgesic,cardiovascular protection,and learning and memory enhancement.This article systematically reviewed the literature related to the chemical constituents and pharmacological activities of L.sinense Oliv.Cv.Chaxiong over the past 30 years,providing a reference for its future development and utilization.

关 键 词：茶芎 化学成分 药理活性 

分 类 号：R282.71[医药卫生—中药学]