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作 者:梁彩霞 LIANG Caixia(Department of Pharmacy,Quanzhou Guoyu Hospital,Quanzhou 362400,Fujian,China)
出 处:《糖尿病新世界》2024年第13期71-73,共3页Diabetes New World
摘 要:目的分析老年糖尿病患者应用阿卡波糖片结合甘精胰岛素治疗的有效性。方法选取2021年3月—2023年2月泉州国宇医院收治的80例老年糖尿病患者为研究对象,根据不同治疗方案分为探究组和一般组,各40例。一般组利用甘精胰岛素治疗,探究组采取阿卡波糖片结合甘精胰岛素治疗。对比两组治疗有效率、治疗前后血糖水平、不良反应发生率。结果探究组治疗有效率为97.50%(39/40),高于一般组的77.50%(31/40),差异有统计学意义(χ^(2)=7.314,P<0.05)。治疗前,两组血糖水平对比,差异无统计学意义(P均>0.05);治疗后,探究组血糖水平(空腹血糖、餐后2 h血糖、糖化血红蛋白)低于一般组,差异有统计学意义(P均<0.05)。探究组不良反应发生率为2.50%(1/40),低于一般组的25.00%(10/40),差异有统计学意义(χ^(2)=8.538,P<0.05)。结论阿卡波糖片结合甘精胰岛素治疗老年糖尿病的效果显著,可改善患者的血糖水平,治疗安全性较高。Objective To analyze the effectiveness of acarbose tablets combined with insulin glargine in the treatment of elderly patients with diabetes.Methods A total of 80 elderly patients with diabetes mellitus admitted to Quanzhou Guoyu Hospital from March 2021 to February 2023 were selected as the research objects.According to different treatment plans,they were divided into inquiry group and general group,with 40 cases in each group.The general group was treated with insulin glargine,and the inquiry group was treated with acarbose tablets combined with insulin glargine.The effective rate of treatment,blood glucose levels before and after treatment,and incidence of adverse reactions were compared between the two groups.Results The effective rate of treatment in the inquiry group was 97.50%(39/40),which was higher than 77.50%(31/40)in the general group,and the difference was statistically significant(χ^(2)=7.314,P<0.05).Before treatment,there were no significant difference in blood glucose levels between the two groups(all P>0.05).After Treatment,the blood glucose levels(fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin A1c)of the inquiry group were lower than those of the general group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the inquiry group was 2.50%(1/40),which was lower than 25.00%(10/40)in the general group,and the difference was statistically significant(χ^(2)=8.538,P<0.05).Conclusion The effect of acarbose tablets combined with insulin glargine in the treatment of elderly diabetes mellitus is significant,which can improve the blood glucose level of patients,and the treatment safety is high.
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