一例重度溃疡性结肠炎合并肠外表现患者的药学监护  

Pharmaceutical monitoring of a patient with severe ulcerative colitis complicated with extraintestinal manifestations

作　　者：白凤 丁瑞峰[2] 刘欣[3] 董志强 BAI Feng;DING Rui-feng;LIU Xin(Pharmacy Department of the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014010,China;不详)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院药学部,内蒙古包头014010 [2]内蒙古科技大学包头医学院第一附属医院消化内科,内蒙古包头014010 [3]西安交通大学第二附属医院消化内科,西安710000

出　　处：《中国处方药》2024年第9期75-77,共3页Journal of China Prescription Drug

基　　金：内蒙古自治区自然科学基金项目(2024QN08090);包头医学院科学研究基金项目(BYJJ-QWB 202226)。

摘　　要：目的对1例重度溃疡性结肠炎合并坏疽性脓皮病、膝关节肿痛、踝关节肿痛患者的治疗方案进行分析,临床药师协助医生制定药物治疗与监护计划,保障患者用药安全、合理、有效。方法结合患者的疾病史,根据药物治疗效果及不良反应,与医生沟通药物的选择、用药剂量及药物使用原则,对患者治疗方案由英夫利西单抗转换为托法替布治疗的风险与获益进行评估,并对患者进行用药教育。结果临床药师从药学角度出发,参与临床治疗,优化药物治疗方案,提高了患者对疾病的认识和依从性,保障了用药安全。结论临床药师参与制定药学治疗方案和药学监护,为患者提供个性化的用药服务,提高临床用药的安全性、有效性,提升患者就医幸福感。Objective To analyze the treatment plan of a patient with severe ulcerative colitis complicated with gangrenous pyoderma,knee joint swelling and pain,and ankle joint swelling and pain.Clinical pharmacists assist doctors in formulating medication treatment and monitoring plans to ensure the patient's medication safety,rationality,and effectiveness.Methods Based on the patient's medical history and the effectiveness and adverse reactions of drug treatment,communicate with doctors about the selection,dosage,and principles of drug use,evaluate the risks and benefits of converting the patient's treatment plan from infliximab to tofacitinib,and provide medication education to the patient.Results From a pharmaceutical perspective,clinical pharmacists participated in clinical treatment,optimized drug treatment plans,improved patient awareness and compliance with the disease,and ensured medication safety.Conclusion Clinical pharmacists participate in the formulation of pharmaceutical treatment plans and pharmaceutical monitoring,providing personalized medication services for patients,improving the safety and effectiveness of clinical medication,and enhancing patients'sense of happiness when seeking medical treatment.

关 键 词：英夫利西单抗 溃疡性结肠炎 托法替布 坏疽性脓皮病 膝关节肿痛 踝关节肿痛 

分 类 号：R969.3[医药卫生—药理学]