弹性成像术评价多囊卵巢综合征患者孕期宫颈机能的价值  

The Value of Elastography in Evaluating Cervical Function in Patients with Polycystic Ovary Syndrome During Pregnancy

作　　者：孙炎武 魏兆莲[1] Sun Yanwu;Wei Zhaolian(Department of Obstetrics and Gynecology,The First Affiliated Hospital of Anhui Medical University,Hefei 230000,Anhui)

机构地区：[1]安徽医科大学第一附属医院妇产科,合肥市230000

出　　处：《中国超声医学杂志》2024年第9期1038-1042,共5页Chinese Journal of Ultrasound in Medicine

基　　金：2022年度安徽省临床医学研究转化专项项目(No.202204295107020029)。

摘　　要：目的探讨宫颈弹性成像术(E-cervix)对多囊卵巢综合征(PCOS)患者宫颈机能的评价及临床价值。方法采取回顾性研究,选择100例妊娠中晚期出现流产或早产征象的PCOS患者临床资料作为研究对象。根据患者是否合并宫颈功能不全(CI)进行分组,将并发CI患者临床资料纳入POCS-CI组(n=34),将未合并CI患者临床资料纳入POCS-非CI合并组(n=66)。结果POCS-CI组孕前体质量指数、T、ECI、IOS、IOS/EOS水平高于POCS-非CI合并组,CL、HR低于POCS-非CI合并组(P<0.05);二元Logistic回归分析结果显示,孕前体质量指数、T、ECI、IOS/EOS高水平是POCS患者并发CI的危险因素(OR=1.408、1.465、3.600、85.974,P<0.05);CL、HR高水平是POCS患者并发CI的保护因素(OR=0.088、0.906,P<0.05);绘制ROC曲线结果显示,T、CL、ECI、IOS/EOS、HR及联合检验预测POCS患者并发CI的AUC分别为0.706、0.714、0.640、0.775、0.744、0.952,其中联合检测价值最高。结论宫颈弹性成像术能够有效预测PCOS患者CI发生风险,其中孕前体质量指数、T、ECI、IOS/EOS、CL、HR是PCOS伴CI的影响因素。Objective To investigate the evaluation and clinical value of cervical elastography(E-cervix)on cervi-cal function in patients with polycystic ovary syndrome(PCOS).Methods A retrospective study was conducted to se-lect the clinical data of 100 PCOS patients with signs of abortion or premature delivery in the middle and late pregnan-cy as the research objects.The clinical data of patients with cervical insufficiency(CI)were included in the POCS-CI group(n=34),and the clinical data of patients without CI were included in the POCS-non CI group(n=66).Results The pre-pregnancy body mass index,T,ECI,IOS and IOS/EOS levels in the POCS-CI group were higher than those in the POCS-non CI combined group,and CL and HR were lower than those in the POCS-non CI combined group(P<0.05);Binary Logistic regression analysis showed that pre-pregnancy body mass index,T,ECI,and high IOS/EOS levels were risk factors for CI in POCS patients(OR=1.408,1.465,3.600,85.974,P<0.05).The high lev-els of CL and HR were the protective factors of CI in POCS patients(OR=0.088,0.906,P<0.05).The results of ROC curve showed that the AUC of T,CL,ECI,IOS/EOS,HR and combined test for predicting CI in POCS pa-tients were 0.706,0.714,0.640,0.775,0.744 and 0.952,respectively,and the combined test had the highest val-ue.The decision curve was drawn.Conclusions Cervical elastography can effectively predict the risk of CI in PCOS patients.Pre-pregnancy body mass index,T,ECI,IOS/EOS,CL and HR are the influencing factors of CI in PCOS patients.

关 键 词：多囊卵巢综合征 宫颈功能不全 宫颈弹性成像术 预测 

分 类 号：R711.75[医药卫生—妇产科学] R445.1[医药卫生—临床医学] R714.2