^(18)F-MFBG新型正电子心脏交感神经显像剂的最新研究进展  

Update Research of ^(18)F-MFBG Novel Positron Cardiac Sympathetic Imaging Agent

作　　者：汪娇[1] 李剑明[1] WANG Jiao;LI Jianming(Department of Nuclear Medicine,TEDA International Cardiovascular Hospital,Tianjin 300457,China)

机构地区：[1]泰达国际心血管病医院核医学科,天津300457

出　　处：《心血管病学进展》2024年第9期802-805,共4页Advances in Cardiovascular Diseases

基　　金：天津市医学重点学科(专科)建设项目(TJYXZDXK-020A);天津市滨海新区卫生健康委员会科技项目(2023BWKY022)。

摘　　要：自主神经系统在调节心血管功能方面起着非常重要的作用,完整的神经支配是心血管功能正常的基础。心脏神经系统的改变通常出现在临床症状之前。心脏交感神经显像可直观显示心脏交感神经的完整性和功能状态,是评价心脏交感神经功能的灵敏指标,能够灵敏地反映心脏自主神经功能的完整性、神经元的分泌功能及活性,对心脏疾病的早期诊断和及时干预有重要的临床价值。近年来^(18)F-MFBG新型正电子心脏交感神经显像剂发展迅速,具有潜在的良好应用前景,现综述该显像剂相关研究的最新进展。The autonomic nervous system plays a vital role in regulating cardiovascular function,complete innervation is the basis of normal cardiovascular function.Changes in the cardiac nervous system usually occur before clinical symptoms.Cardiac sympathetic imaging can directly display the integrity and functional status of the cardiac sympathetic nerve and is a sensitive index to evaluate cardiac sympathetic nerve function.It can sensitively reflect the integrity of cardiac autonomic nerve function and the secretory function and activity of neurons.It has significant clinical value for early diagnosis and timely heart disease intervention.In recent years,^(18)F-MFBG novel positron cardiac sympathetic imaging agent has developed rapidly and has good potential application prospects.This article reviews the latest research progress on this agent.

关 键 词：氟放射性同位素 放射性示踪剂 正电子发射体层成像 心脏 交感神经系统 

分 类 号：R817.4[医药卫生—影像医学与核医学] R54[医药卫生—放射医学]