非高密度脂蛋白胆固醇与动脉粥样硬化性心血管疾病关系的研究进展  

The Relationship Between Non-High-Density Lipoprotein Cholesterol and Atherosclerotic Cardiovascular Disease

作　　者：丁芳芳 廖付军 鲍海龙 李洁琪 DING Fangfang;LIAO Fujun;BAO Hailong;LI Jieqi(Department of Cardiovascular Medicine,The Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China)

机构地区：[1]贵州医科大学附属医院心血管内科,贵州贵阳550004

出　　处：《心血管病学进展》2024年第9期806-810,共5页Advances in Cardiovascular Diseases

基　　金：贵州省科技计划项目(黔科合支撑[2021]一般063);贵州省卫生健康委员会科学技术基金项目(gzwkj2021-112)。

摘　　要：近年来随着研究的深入,非高密度脂蛋白胆固醇逐渐受到广泛关注。越来越多的证据显示,其在检测的全面性、准确性和稳定性方面相较于低密度脂蛋白胆固醇具有更明显的优势,且预测动脉粥样硬化性心血管疾病(ASCVD)风险的能力更强,目前已成为评估和治疗ASCVD的主要指标之一。中国血脂管理指南(2023版)也提高了对其的推荐级别,将其作为防治ASCVD的次要干预靶点。现就非高密度脂蛋白胆固醇与ASCVD关系的研究进展进行综述。In recent years,with the deepening of research,non-high-density lipoprotein cholesterol has gradually attracted widespread attention.More and more evidence shows that its comprehensiveness,accuracy and stability in detection have more obvious advantages than low-density lipoprotein cholesterol,and its ability to predict the risk of atherosclerotic cardiovascular disease(ASCVD)is stronger.At present,it has become one of the main indicators for evaluating and treating ASCVD.The Chinese Guidelines for Blood Lipid Management(2023 Edition)have also raised its recommendation level as a secondary intervention target for the prevention and treatment of ASCVD.This article reviews the research progress on the relationship between non-high-density lipoprotein cholesterol and ASCVD.

关 键 词：非高密度脂蛋白胆固醇 低密度脂蛋白胆固醇 动脉粥样硬化 心血管疾病 

分 类 号：R543.5[医药卫生—心血管疾病]