兽用mRNA疫苗的研究进展  

Progress in research on veterinary mRNA vaccines

作　　者：庞帅赛 王诗诗 刘光清[1] 孟春春[1] PANG Shuaisai;WANG Shishi;LIU Guangqing;MENG Chunchun(Companion Animal Biosecurity Risk Early Warning,Prevention and Control Technology Innovation Team,Shanghai Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Shanghai 200241,China)

机构地区：[1]中国农业科学院上海兽医研究所伴侣动物生物安全风险预警及防控技术创新团队,上海200241

出　　处：《畜牧与兽医》2024年第10期114-121,共8页Animal Husbandry & Veterinary Medicine

基　　金：“十四五”重点研发计划项目(2022YFD1800100);国家自然基金面上项目(32272982);上海市自然基金项目(23ZR1477100)。

摘　　要：疫苗接种是动物日常保健中必不可少的。近年来,随着免疫学研究的持续发展和分子生物学技术的不断完善,mRNA疫苗在动物传染性疾病防治方面取得了一定的成果,广受各方关注。为加深对mRNA疫苗的了解,本文将从mRNA疫苗主要类型、结构特征、免疫机制、独特优势及其在兽用领域的研究现状等几个方面,对兽用mRNA疫苗目前的主要研究进展作一系统性综述,以期为后续开展mRNA疫苗相关的研究提供参考资料。Vaccination is essential in the daily health care of both farm animals and companion animals.The continual advancement of im-munological studies and the augmentation of molecular biology technology have enabled messenger RNA(mRNA)vaccines to attain certain outcomes in the prevention and treatment of infectious diseases in animals,thus drawing extensive notice in recent times.In order to deepen the understanding of mRNA vaccines,this paper will summarize and make a systematic review on the current progress in research on veterina-ry mRNA vaccines,including the main types of mRNA vaccines,their structural characteristics,immune mechanisms,unique advantages,and the current status of research in the veterinary field,with a view to providing reference materials for future studies on mRNA vaccines.

关 键 词：mRNA疫苗 兽用疫苗 免疫 动物传染病 

分 类 号：S859[农业科学—临床兽医学]