高液体衰减反转恢复序列与卵圆孔未闭的相关性分析  

Correlation between high fluid attenuation inversion recovery sequence and patent foramen ovale

作　　者：石子玉 杨呈伟 孔慧慧 刘浩 高琦 程志英 李欣 齐伟伟 蒋小玲 奚娟 黄连军 SHI Ziyu;YANG Chengwei;KONG Huihui;LIU Hao;GAO Qi;CHENG Zhiying;LI Xin;QI Weiwei;JIANG Xiaoling;XI Juan;HUANG Lianjun(Department of Imaging and Intervenional,Shanghai Delta Hospital,Shanghai 201702,China)

机构地区：[1]上海德达医院,201702 [2]首都医科大学附属北京友谊医院

出　　处：《心肺血管病杂志》2024年第9期967-971,共5页Journal of Cardiovascular and Pulmonary Diseases

基　　金：上海市青浦区第五轮人才培养计划(TZ2023-13)。

摘　　要：目的:探讨中青年健康体检人群颅脑磁共振(magnetic resonance imaging,MRI)高液体衰减反转恢复序列(fluid attenuated inversion recovery,FLAIR)信号与卵圆孔未闭(patent foramen ovale,PFO)的相关性。方法:回顾性选取2021年1月至2023年3月,上海德达医院完成头颅MRIFLAIR检查和在静息状态、Valsalva动作下完成c-TTE检查(右心声学造影)的中青年体检者,分为两组,A组高Flair信号组和B组无高Flair信号组。比较高FLAIR信号和PFO的相关性。结果:共有184例患者纳入本研究,年龄18~55岁,平均(40.4±8.5)岁,两组患者性别、年龄、吸烟史、饮酒史、肥胖病史、患有呼吸睡眠综合征及冠心病史等的发生率差异均无统计学意义(P>0.05),详见表1,两组患者偏头痛病史的发生率差异有统计学意义(P=0.00)。A组患有PFO的患者所占比例明显高于B组,差异有统计学意义(P <0.001)。结论:中青年在体检中发现脑白质内高FLAIR信号的影像信息应该受到重视,进一步明确是否有卵圆孔未闭是筛查其病因的重要工作,偏头痛与卵圆孔有着明显的关联性。为PFO的诊治提供有效的预判及应对措施。Objective:To investigate the correlation between high brain magnetic resonance imaging(MRI) fluid attenuated inversion recovery(FLAIR) signal and patent foramen ovale(PFO) in young and middle-aged people.Methods:Retrospectively selected young and middle-aged patients who completed skull MRI-FLAIR examination and c-TTE examination(right cardiac imaging under resting state) in Shanghai Delta Hospital from January 2021 to March 2023 were divided into two groups.Group A with high Flair signal and group B without high Flair signal.To compare the correlation between high FLAIR signal and PFO,data processing was performed using SPSS 27.0 statistical software and count data by t-test.Results:A total of 184 patients,age 18 to 55 years,mean age(40.4± 8.5)years,gender,age,smoking,drinking,obesity,respiratory sleep syndrome and coronary heart disease history were not different in both groups(P> 0.05),and the incidence of migraine in both groups(P=0.004).The proportion of patients with PFO in Group A was significantly higher than that in group B,with significant differences(P<0.001).Conclusion:Young and middle-aged people who found high FLAIR signal in the white matter during physical examination should be paid attention to,and further clarify whether there is patent foramen ovale is an important work to screen the cause.Migraine and foramen ovale have an obvious correlation.To provide effective prediction and countermeasures for the diagnosis and treatment of PFO.

关 键 词：磁共振 卵圆孔未闭 高液体衰减反转恢复序列信号 右心声学造影 

分 类 号：R54[医药卫生—心血管疾病]