产后出血产妇采取卡前列素氨丁三醇联合缩宫素治疗后对其出血量的影响  

The effect of combination therapy with carboprost tromethamine and oxytocin on bleeding volume of parturients with postpartum hemorrhage

作　　者：周超[1] 李丽丽[1] ZHOU Chao;LI Li-li(Intensive Care Unit,Tai'an Central Hospital Affiliated to Qingdao University,Tai'an 271000,China)

机构地区：[1]青岛大学附属泰安市中心医院重症医学科,271000

出　　处：《中国实用医药》2024年第18期15-18,共4页China Practical Medicine

摘　　要：目的探讨产后出血产妇采取卡前列素氨丁三醇联合缩宫素治疗后对其出血量的影响。方法100例产后出血产妇作为研究对象,根据治疗方式不同分为对照组(50例,采取缩宫素治疗)和观察组(50例,采取卡前列素氨丁三醇联合缩宫素治疗)。比较两组产妇的出血量、不良反应发生情况、治疗效果。结果治疗后2、12、24、36 h,观察组的出血量分别为(235.89±26.12)、(272.31±29.45)、(288.89±25.20)、(299.31±31.45)ml,均少于对照组的(306.45±22.24)、(351.81±31.81)、(386.45±26.24)、(405.81±31.81)ml,差异明显(P<0.05)。治疗后,观察组产妇的不良反应发生率2.00%低于对照组的14.00%,差异明显(P<0.05)。治疗后,观察组的总有效率98.00%高于对照组的84.00%,差异明显(P<0.05)。结论对产后出血产妇采用卡前列素氨丁三醇联合缩宫素治疗后,能降低产妇的出血量,减少不良反应的发生,提高治疗效果,影响较大。Objective To explore the effect of combination therapy with carboprost tromethamine and oxytocin on bleeding volume of parturients with postpartum hemorrhage.Methods According to different treatment methods,100 parturients with postpartum hemorrhage were divided into a control group(50 cases,treated with oxytocin)and an observation group(50 cases,treated with carboprost tromethamine and oxytocin).The bleeding volume,the occurrence of adverse reactions and the therapeutic effect were compared between the two groups.Results At 2,12,24 and 36 h after treatment,the bleeding volume in the observation group were(235.89±26.12),(272.31±29.45),(288.89±25.20)and(299.31±31.45)ml,which were significantly lower than(306.45±22.24),(351.81±31.81),(386.45±26.24)and(405.81±31.81)ml in the control group,and the difference was significant(P<0.05).After treatment,the incidence of adverse reactions in the observation group was 2.00%,which was significantly lower than 14.00%in the control group(P<0.05).After treatment,the total effective rate of 98.00%in the observation group was higher than 84.00%in the control group,and the difference was significant(P<0.05).Conclusion For parturients with postpartum hemorrhage,the combination of carboprost tromethamine and oxytocin can reduce the bleeding volume,lower the occurrence of adverse reactions,improve the therapeutic effect,and have a significant impact.

关 键 词：产后出血 产妇 卡前列素氨丁三醇 缩宫素 出血量 

分 类 号：R714.461[医药卫生—妇产科学]