不同浓度曲安奈德联合局部红光照射治疗手术切除后耳郭瘢痕疙瘩的效果分析  

Curative effect of different doses of triamcinolone combined with local red light irradiation in auricle keloid after surgical excision

作　　者：赵颜颜 李谊 ZHAO Yanyan;LI Yi(Department of Otolaryngology,the 988th Hospital of Joint Logistics Support Force,Henan Province,454150,China)

机构地区：[1]联勤保障部队第九八八医院耳鼻喉科,河南焦作454150

出　　处：《中国医疗美容》2024年第8期64-67,共4页China Medical Cosmetology

基　　金：河南省医学科技攻关省部共建重点项目(SBGJ202102207)。

摘　　要：目的 探讨不同曲安奈德剂量联合局部红光照射治疗手术切除后的耳郭瘢痕疙瘩患者中的应用效果。方法 选取2021年1月至2023年5月在联勤保障部队第九八八医院耳鼻喉科行手术切除的60例耳郭瘢痕疙瘩患者,采用曲安奈德注射液50 mg/1.5 mL联合局部红光照射治疗的30例患者纳入高浓度组。采用曲安奈德注射液50 mg/3.0 mL联合局部红光照射治疗的30例患者纳入低浓度组。随访6个月,比较两组患者治疗效果、心理状态评分、瘢痕情况及不良反应。结果 高浓度组患者治疗的总有效率为95.00%,显著高于低浓度组的77.50%(P<0.05);高浓度组患者焦虑自评量表、抑郁自评量表、温哥华瘢痕量表评分均降低,且低于低浓度组(P<0.05);两组患者不良反应比较差异无统计学意义(P>0.05)。结论 高浓度曲安奈德联合局部红光照射可显著提高耳郭瘢痕疙瘩手术切除患者的治疗效果,改善患者心理状态及瘢痕情况,安全性较高。Objective To explore the curative effect of different doses of triamcinolone combined with local red light irradiation in patients with auricle keloid after surgical excision.Methods From January 2021 to may 2023,60 patients with keloids in the auricle underwent surgical resection in the Department of Otolaryngology of the 988 Hospital of the joint service support force.60 patients with ear scar tissue were included in the high concentration group,and 30 patients were treated with a combination of 50 mg/1.5 mL of triamcinolone acetonide injection and local red light irradiation.Thirty patients treated with 50 mg/3.0 mL of dexamethasone injection combined with local red light irradiation were included in the low concentration group.Follow up for 6 months,compare the treatment efficacy,psychological status scores,scar condition,and adverse reactions between the two groups of patients.Results The total effective rate of treatment for patients in the high concentration group was 95.00%,significantly higher than the 77.50%in the low concentration group(P<0.05).After treatment,scores of SAS,SDS and VSS were decreased in high-dose group,lower than those in low-dose group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions High-dose triamcinolone combined with local red light irradiation can significantly improve curative effect,improve psychological state and scars in patients with auricle keloid after surgical excision,which has high safety.

关 键 词：曲安奈德注射液 红光照射治疗 耳郭 瘢痕疙瘩 

分 类 号：R622[医药卫生—整形外科]