Feasibility study of the photonuclear reaction cross section of medical radioisotopes using a laser Compton scattering gamma source  

作　　者：Yu-Ning Gu Wei-Juan Zhao Xi-Guang Cao Yu-Xuan Yang Ting-Kai Ma Zheng-Li Liao Fei-Long Xu Yu-Gang Ma 

机构地区：[1]School of Physics and Microeletronics,Zhengzhou University,Zhengzhou 450001,China [2]Shanghai Advanced Research Institute,Chinese Academy of Sciences,Shanghai 201210,China [3]Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800,China [4]University of Chinese Academy of Sciences,Beijing 100049,China [5]School of Nuclear Science and Technology,University of South China,Hengyang 421001,China [6]Key Laboratory of Nuclear Physics and Ion-beam Application(MOE),Institute of Modern Physics,Fudan University,Shanghai 200433,China [7]Shanghai Research Center for Theoretical Nuclear Physics,NSFC and Fudan University,Shanghai 200438,China

出　　处：《Nuclear Science and Techniques》2024年第9期168-177,共10页核技术（英文）

基　　金：supported by the Strategic Priority Research Program of the CAS(No.XDB34030000);National Natural Science Foundation of China(No.11975210 and No.U1832129);National Key Research and Development Program of China(No.2022YFA1602404);Youth Innovation Promotion Association CAS(No.2017309).

摘　　要：In recent years,the gap between the supply and demand of medical radioisotopes has increased,necessitating new methods for producing medical radioisotopes.Photonuclear reactions based on gamma sources have unique advantages in terms of producing high specific activity and innovative medical radioisotopes.However,the lack of experimental data on reaction cross sections for photonuclear reactions of medical radioisotopes of interest has severely limited the development and production of photonuclear transmutation medical radioisotopes.In this study,the entire process of the generation,decay,and measurement of medical radioisotopes was simulated using online gamma activation and offline gamma measurements combined with a shielding gamma-ray spectrometer.Based on a quasi-monochromatic gamma beam from the Shanghai Laser Electron Gamma Source(SLEGS),the feasibility of this measurement of production cross section for surveyed medi-cal radioisotopes was simulated,and specific solutions for measuring medical radioisotopes with ultra-low production cross sections were provided.The feasibility of this method for high-precision measurements of the reaction cross section of medical radioisotopes was demonstrated.

关 键 词：Medical radioisotope Photonuclear reaction GEANT4 Shanghai Laser Electron Gamma Source(SLEGS) Low-background gamma-ray spectrometer 

分 类 号：R817[医药卫生—影像医学与核医学]