维生素D在儿童原发性肾病综合征中的保护作用及应用策略研究进展  

Research progress on the protective effect and application strategy of vitamin D in children with primary nephrotic syndrome

作　　者：潘瑞英 PAN Ruiying(Department of Pediatrics,924th Hospital of the PLA Joint Logistics Support Force,Guangxi Zhuang Autonomous Region,Guilin 541002,China)

机构地区：[1]中国人民解放军联勤保障部队第九二四医院儿科,广西桂林541002

出　　处：《妇儿健康导刊》2024年第18期17-22,共6页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z-C20221056)。

摘　　要：原发性肾病综合征是儿童最常见的肾小球疾病之一,其病理生理的改变和长期的糖皮质激素治疗影响维生素D代谢。本文对儿童原发性肾病综合征与维生素D缺乏的关系、维生素D补充与骨保护及肾脏保护作用,以及原发性肾病综合征儿童维生素D营养状态的临床评估、筛查、预防、治疗和安全性的应用进行综述,为原发性肾病综合征儿童科学、安全、有效应用维生素D提供参考。Primary nephrotic syndrome is one of the most common glomerular diseases in children,and its pathophysiological changes and long-term glucocorticoid therapy affect vitamin D metabolism.This article reviews the relationship between primary nephrotic syndrome in children and vitamin D deficiency,vitamin D supplementation and bone protection,kidney protection,as well as the clinical determination,screening,prevention,treatment of vitamin D nutritional status,and safety application of vitamin D in children with primary nephrotic syndrome,in order to provide reference for the scientific,safe,and effective application o f vitamin D in children with primary nephrotic syndrome.

关 键 词：原发性肾病综合征 维生素D缺乏 维生素D补充 儿童 

分 类 号：R726.9[医药卫生—儿科]