疤痕子宫妊娠行米索前列醇联合人工流产手术治疗的有效性及安全性  

Efficacy and Safety of Misoprostol Combined with Induced Abortion in the Treatment of Scarred Uterine Pregnancy

作　　者：赵婷 陈芳 ZHAO Ting;CHEN Fang(Department of Obstetrics and Gynecology,Wuhan Ren'ai Hospital,Wuhan 430000,Hubei Province,China)

机构地区：[1]武汉仁爱医院妇产科,湖北武汉430000

出　　处：《罕少疾病杂志》2024年第9期94-96,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的 探讨米索前列醇联合人工流产手术在疤痕子宫妊娠治疗中的应用效果。方法 采集2020年1月-2022年12月收治的疤痕子宫妊娠患者120例,基于“随机数字表法”1:1分组,划分为对照组(实施人工流产手术)与观察组(人工流产手术联合米索前列醇),各60例;对比两组手术相关指标、宫颈软化程度、术后疼痛程度、并发.症发生率、生活质量。结果 观察组较对照组手术用时、术后流血时间相对短,术中出血量相对低(P<0.05);观察组宫颈软化优良率较对照组明显高(P<0.05);观察组术后VAS评分、并发症发生率低于对照组(P<0.05);术后,两组SF-36评分均大幅度升高,其中观察组相对更高(P<0.05)。结论 疤痕子宫妊娠患者实施米索前列醇联合人工流产手术治疗,相比单纯人工流产手术,可取得良好的宫颈扩张效果,降低术中出血量及减轻手术创伤,缓解术后疼痛,降低术后并发症几率。Objective To investigate the effect of misoprostol combined with induced abortion in the treatment of scar uterine pregnancy.Methods A total of 120 patients with scarred uterine pregnancy admitted from January 2020 to December 2022 were collected and divided into control group(induced abortion)and observation group(induced abortion combined with misoprostol),60 cases each,based on the"random number table method"(1:1).The indexes related to surgery,degree of cervical softening,degree of postoperative pain,incidence of complications and quality of life were compared between the two groups.Results Compared with the control group,the operation time and postoperative bleeding time of the observation group were shorter,and the amount of intraoperative bleeding was lower(P<0.05).The good and good rate of cervical softening in observation group was significantly higher than that in control group(P<0.05).VAS score and complication rate of observation group were lower than control group(P<0.05).After surgery,SF-36 scores were significantly increased in both groups,and the observation group was relatively higher(P<0.05).Conclusions Compared with artificial abortion alone,misoprostol combined with artificial abortion can achieve good cervical dilation effect,reduce intraoperative blood loss,reduce surgical trauma,relieve postoperative pain,and reduce postoperative complications in patients with scarred uterus pregnancy.

关 键 词：疤痕子宫妊娠 米索前列醇 人工流产手术 有效性 安全性 

分 类 号：R714[医药卫生—妇产科学]