AngioJet机械性血栓抽吸术治疗急性肺动脉血栓栓塞  

AngioJet Mechanical Thrombus Aspiration for the Treatment of Acute Pulmonary Thromboembolism

作　　者：姜鹏 孙建锋 梅菲 Jiang Peng;Sun Jian feng;Mei Fei(Department of Vascular Surgery,Yichang Central People's Hospital,The First College of Clinical Medical Science,China Three Gorges University,Yichang 443003,China;Hubei Key Laboratory of Ischemic Cardiovascular Disease,Yichang 443003,China;Hubei Provincial Clinical Research Center for Ischemic Cardiovascular Disease,Yichang 443003,China)

机构地区：[1]三峡大学第一临床医学院[宜昌市中心人民医院]血管外科,湖北宜昌443003 [2]缺血性心血管病湖北省重点实验室,湖北宜昌443003 [3]湖北省缺血性心血管疾病临床医学研究中心,湖北宜昌443003

出　　处：《巴楚医学》2024年第3期19-22,共4页Bachu Medical Journal

基　　金：湖北省自然科学基金青年项目(No:2022CFB622);宜昌市医疗卫生研究项目(No:A23-1-014)。

摘　　要：急性肺动脉血栓栓塞(PTE)起病隐匿、发病急、症状重、死亡率高,在全球致死性心血管疾病中高居第3位。目前急性PTE的治疗方式主要包括抗凝、溶栓、经皮腔内吸栓和手术取栓等。血流动力学稳定的PTE首选抗凝治疗,血流动力学不稳定的PTE推荐抗凝联合全身溶栓治疗,但是出血风险高,溶栓效果有限,因此逐渐被经皮腔内吸栓治疗所取代。AngioJet机械性血栓抽吸术可迅速清除血栓、降低肺动脉压、改善右心功能以及纠正低氧血症,显著提高患者生活质量和存活率。本文通过介绍AngioJet机械性血栓抽吸术治疗PTE的手术操作过程,探讨术中可能出现的问题及解决方案。Acute pulmonary thromboembolism(PTE),with its insidious onset,acute morbidity,severe symptoms,and high mortality,is the third most common cardiovascular disease worldwide.Current treatment modalities for acute PTE include anticoagulation,thrombolysis,percutaneous endovascular aspiration,and surgical thrombectomy.Anticoagulation is generally preferred for hemodynamically stable PTE,and anticoagulation and systemic thrombolysis are generally recommended for hemodynamically unstable PTE,but the high risk of bleeding and limited efficacy of thrombolysis are gradually being replaced by percutaneous endovascular aspiration.AngioJet mechanical thrombus aspiration provides rapid thrombus removal,reduces pulmonary artery pressure,improves right heart function,and corrects hypoxemia,significantly improving patient quality of life and survival.This article describes the surgical procedure of AngioJet mechanical thrombus aspiration for the treatment of PTE and discusses potential intraoperative problems and solutions.

关 键 词：肺动脉血栓栓塞 AngioJet机械性血栓抽吸术 深静脉血栓形成 

分 类 号：R654.3[医药卫生—外科学]