基于“脾脑相关”理论探讨从脾论治糖尿病认知功能障碍的理论基础  

Discussion on Theoretical Basis of Treating Diabetes-associated Cognitive Decline from Spleen Based on"Correlation between Spleen and Brain"

作　　者：陆霖峰 周雯[1] 王钰[2,3,4] 战丽彬 LU Linfeng;ZHOU Wen;WANG Yu;ZHAN Libin(School of Traditional Chinese Medicine&School of Integrated Chinese and Western Medicine,Modern Research Laboratory of Spleen Visceral Manifestations Theory,Nanjing University of Chinese Medicine,Nanjing 210023,Jiangsu,China;Centre for Innovative Engineering Technology in Traditional Chinese Medicine,Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Key Laboratory of Liaoning Province for Traditional Chinese Medicine Spleen-Viscera-State Modern Research,Shenyang 110847,Liaoning,China;Key Laboratory of Ministry of Education for Traditional Chinese Medicine Viscera-State Theory and Applications,Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)

机构地区：[1]南京中医药大学中医学院·中西医结合学院,江苏南京210023 [2]辽宁中医药大学中医药创新工程技术中心,辽宁沈阳110847 [3]辽宁省中医脾脏象现代研究重点实验室,辽宁沈阳110847 [4]辽宁中医药大学中医脏象理论及应用教育部重点实验室,辽宁沈阳110847

出　　处：《中华中医药学刊》2024年第10期153-156,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金重点项目(81730111);国家中医药领军人才岐黄学者支持项目(国中医药人教函[2022]6号);江苏省自然科学基金青年科学基金项目(BK20210688)。

摘　　要：从中医“脾脑相关”理论,糖尿病认知功能障碍(diabetes-associated cognitive decline,DACD)的中医理论、基础研究和临床实践出发,阐述从脾论治DACD的依据和策略。DACD其病因病机复杂,病位在脑,与多脏相关,但根于脾脏。脾气亏虚,脑髓失充,痰蒙清窍,湿瘀阻络是脾功能失司导致认知功能障碍的关键,补脾健脾应当贯穿于DACD治疗的全过程。基于“脾脑相关”理论,对脾脏和脑的生理功能、病理过程相关性进行分析,从脾脑相关联角度揭示DACD的病因、病机及治疗思路,并阐释“脾脑相关”理论的现代生物学内涵。From the theory of“correlation between spleen and brain”in TCM,the TCM theory of diabetes-associated cognitive decline(DACD),basic research and clinical practice,it explains the basis and strategy of treating DACD from the spleen theory.DACD has a complex etiology and pathogenesis,and is located in the brain and related to many organs,but is rooted in spleen.Spleen Qi deficiency,brain marrow deficiency,phlegm clouding the clear orifices,and dampness and blood stasis blocking the ligaments are the keys to cognitive decline due to spleen dysfunction.Based on the theory of“correlation between spleen and brain”,this paper analyzed the physiological functions and pathological processes of spleen and brain,revealed the etiology,pathogenesis and treatment ideas of DACD from the perspective of spleen-brain correlation,and explained the modern biological implications of the theory of“correlation between spleen and brain”.It also explained the modern biological connotation of the“correlation between spleen and brain”theory.

关 键 词：糖尿病认知功能障碍 “脾脑相关”理论 从脾论治 理论探讨 

分 类 号：R259.872[医药卫生—中西医结合]