冠状动脉CT成像定量参数与冠心病患者病情严重程度的关系研究  

Correlation Study of Coronary CT Imaging Quantitative Parameters with Illness Severity of Coronar y Heart Disease Patients

作　　者：王天昊 饶胜国 王乔 张惠英 WANG Tian-hao;RAO Sheng-guo;WANG Qiao;ZHANG Hui-ying(Department of Radiology,the Eighth Hospital of Tangshan,Tangshan 063020,Hebei Province,China;Department of Imaging,Affiliated Hospital of North China University of Science and Technology,Tangshan 063020,Hebei Province,China)

机构地区：[1]唐山市第八医院放射科 [2]华北理工大学附属医院影像科,河北唐山063020

出　　处：《中国CT和MRI杂志》2024年第9期76-78,共3页Chinese Journal of CT and MRI

基　　金：河北省医学科学研究重点课题计划(20170928)。

摘　　要：目的研究冠状动脉CT成像定量参数与冠心病患者病情严重程度的关系。方法临床纳入2018年9月至2019年9月期间我院收治的90例冠心病患者作为观察组,另选取同期90例健康志愿者为对照组。对两组研究对象分别进行冠状动脉CT血管成像检查,对比冠心病患者病情程度,分析冠状动脉CT血管成像定量参数与冠心病病情严重程度的关系。结果观察组斑块数量、非钙化斑块体积、钙化斑块体积、斑块总体积、非钙化斑块负荷、钙化斑块负荷、斑块总负荷以及血管狭窄程度均大于对照组,差异均有统计学意义(P<0.05);两组血管体积差异无统计学意义(P>0.05)。观察组LVMI、LVESV、LVEDV以及平均室壁应力均大于对照组,LVEF小于对照组,差异均有统计学意义(P<0.05)。斑块数量、非钙化斑块体积、钙化斑块体积、斑块总体积、非钙化斑块负荷、钙化斑块负荷、斑块总负荷以及血管狭窄程度与LVEF呈负相关,与LVMI、LVESV、LVEDV以及平均室壁应力呈正相关;重建指数与LVEF呈正相关,与LVMI、LVESV、LVEDV以及平均室壁应力呈负相关,均P<0.05。血管体积与心功能水平均无相关性,P>0.05。结论冠状动脉CT成像定量参数与冠心病患者病情严重程度有密切关系,可用于评估患者治疗预后效果。Objective To study the correlation of coronary CT imaging quantitative parameters with illness severity of coronary heart disease patients.Methods 90 coronary heart disease patients treated from September 2018 to September 2019 in our hospital were set as observation group.Over the same time period,90 healthy volunteers were set as control group.Coronary CT angiography was performed.Correlation of CT imaging quantitative parameters with illness severity was analyzed.Results Number of plaques,non-calcified plaque area,calcified plaque area,overall plaque area,non-calcified plaque burden,calcified plaque burden,overall plaque burden and vascular stenosis degree in the observation group were larger than those of control group,with statistically significant difference(P<0.05);vascular volume between groups was not significantly different(P>0.05);LVMI(left ventricular mass index),LVESV(left ventricular end-systolic volume),LVEDV(left ventricular enddiastolic volume)and mean wall stress values in the observation group were larger than those of control group;LVEF(left ventricular ejection fraction)values were smaller than those of control group(P<0.05);number of plaques,non-calcified plaque area,calcified plaque area,overall plaque area,noncalcified plaque burden,calcified plaque burden,overall plaque burden and vascular stenosis degree were negatively correlated with LVEF,but positively correlated with LVMI,LVESV,LVEDV and mean wall stress;reconstruction indicators were positively correlated with LVEF,but positively correlated with LVMI,LVESV,LVEDV and mean wall stress(P<0.05);vascular volume was not related to cardiac function(P>0.05).Conclusion The coronary CT imaging quantitative parameters have close correlation with illness severity,which may be taken for prediction of clinical treatment prognosis.

关 键 词：冠状动脉 CT成像 冠心病 相关性 

分 类 号：R541.4[医药卫生—心血管疾病]