心脏磁共振特征追踪技术定量分析长期过量饮酒者左室心肌应变  

Quantitative Analysis of Left Ventricular Myocardial Strain in Long-Term Excessive Drinkers by Cardiac Magnetic Resonance Imaging Feature Tracking Technology

作　　者：刘新峰[1] 刘江勇[1,2] 廖旦 杨艳 代斌[1,2] 徐睿 王荣品 LIU Xinfeng;LIU Jiangyong;LIAO Dan(Department of Medical Imaging,Guizhou Provincial People's Hospital,Guiyang,Guizhou Province 550002,P.R.China)

机构地区：[1]贵州省人民医院医学影像科,贵阳550002 [2]贵州省省级重点建设学科(医学影像学),贵阳550002

出　　处：《临床放射学杂志》2024年第9期1496-1500,共5页Journal of Clinical Radiology

基　　金：贵州省卫健委科学技术基金项目(编号:gzwkj2021-373号);贵州省科技成果应用及产业化计划项目(黔科合成果-LC[2023]022);贵州省科技厅基金项目(黔科合基础-ZK[2022]一般263);贵州省创新型人才千层次人才计划项目(编号:GZSYQCC[2024]004)。

摘　　要：目的基于心脏磁共振特征追踪(CMR-FT)技术定量分析长期过量饮酒者左室心肌应变损伤程度,并探讨左室心肌各向应变与日均酒精摄入量相关性。方法搜集长期过量饮酒者(饮酒组)42例及21名无饮酒史健康志愿者(对照组)行心脏MRI检查,基于CMR-FT技术分析两组左室整体心肌各向应变、收缩期应变率及峰值位移,视饮酒组日均酒精摄入量,分为轻、中、重度过量饮酒组,采用统计学分析3组左室整体心肌应变参数的差异性。采用Spearman检验对饮酒组左室心肌各向应变与日均酒精摄入量做相关性分析,取P<0.05为差异具有统计学意义。结果饮酒组左室整体心肌径向应变、周向应变、纵向应变分别为(25.15±11.83)%、(-13.94±6.82)%、(-11.99±5.67)%,均较对照组下降,收缩期各向应变率及峰值位移也较对照组不同程度降低(P<0.05)。轻、中、重度饮酒者左室各向应变参数差异具有统计学意义(P<0.05)。左室径向应变与日均酒精摄入量呈负相关(r=-0.78,P<0.001),周向、纵向应变与日均酒精摄入量呈正相关(r值分别为0.77、0.82,P值<0.001)。结论CMR-FT在定量分析过量饮酒导致左室心肌应变能力损伤方面具有一定临床应用价值,饮酒者左室心肌应变能力损伤与日均酒精摄入量有一定相关性。Objective To quantitatively analyze of left ventricular myocardial strain damage in long-term excessive drinkers based on cardiac magnetic resonance feature tracking technology(CMR-FT),and to investigate the correlation between left ventricular myocardial strain and the daily alcohol intake.Methods The 42 long-term excessive drinkers(drinking group)and 21 healthy volunteers(control group)with no drinking history were performed by cardiac magnetic resonance imaging(MRI).Two groups of left ventricular myocardial anisotropic strain,systolic strain rate,and peak displacement were analyzed using CMR-FT.According to the daily alcohol intake of the drinking group,they were divided into mild,moderate,and severe excessive drinking groups.Statistical analysis was used to compare the differences in left ventricular overall myocardial strain parameters among the three groups.The Spearman test were used to analyze the correlation between left ventricular myocardial strain and the daily alcohol intake in the alcohol drinking group,P-value<0.05 was taken as the statistically significant difference.Results The overall radial strain,circumferential strain,and longitudinal strain of the left ventricle in the drinking group were(25.15±11.83)%,(-13.94±6.82)%and(-11.99±5.67)%,respectively,which were lower than those in the control group.The systolic strain rate and peak displacement were also lower than those in the control group(P<0.05).There were significant differences in the parameters of left ventricular isotropic strain between mild,moderate and severe drinkers(P<0.05).Left ventricular radial strain was negatively correlated with the daily alcohol intake(r=-0.78,P<0.001),while circumferential and longitudinal strain was opposite(r values were 0.77 and 0.82,P<0.001).Conclusion CMR-FT has certain clinical application value in quantitative analysis of left ventricular myocardial strain damage caused by excessive alcohol consumption,and left ventricular myocardial strain has a certain correlation with daily alcohol intake.

关 键 词：磁共振 特征踪技术 心肌应变 饮酒 

分 类 号：R445.2[医药卫生—影像医学与核医学] R542.2[医药卫生—诊断学]