1例产褥期使用五加生化胶囊致全身性严重过敏反应的药学监护及分析  

Pharmaceutical monitoring and analysis of a case of severe systemic allergic reaction caused by Wujia shenghua capsules during the postpartum period

作　　者：赵明明 叶轶青[1,2] ZHAO Mingming;YE Yiqing(Dept.of Pharmacy,Jilin Branch,Women’s Hospital,Zhejiang University School of Medicine,Changchun 130042,China;Dept.of Pharmacy,Women’s Hospital,Zhejiang University School of Medicine,Hangzhou 310006,China)

机构地区：[1]浙江大学医学院附属妇产科医院吉林医院药剂科,长春130042 [2]浙江大学医学院附属妇产科医院药剂科,杭州310006

出　　处：《中国药房》2024年第19期2422-2425,共4页China Pharmacy

基　　金：浙江省自然科学基金项目(No.YY22H309478)。

摘　　要：目的 正确识别和应对产褥期使用五加生化胶囊引起的全身性严重过敏反应,为妇产科用药提供参考,促进合理用药。方法 临床药师通过参与1例产褥期使用五加生化胶囊后出现全身性严重过敏反应患者的药学监护及治疗过程,筛查该患者住院期间所用药物,评估该过敏反应与五加生化胶囊的关系及可能的发生原因。结果与结论 该患者全身性严重过敏反应与五加生化胶囊的关系被评估为“很可能相关”,提示过敏体质患者产褥期使用五加生化胶囊时应提高警惕,加强药学监护,尽量避免同时联用相同机制或有潜在相互作用的药物。OBJECTIVE To correctly identify and respond to severe systemic allergic reactions caused by Wujia shenghua capsules during the postpartum period,provide a reference for medication use in obstetrics and gynecology departments,and promote rational drug use.METHODS Clinical pharmacists participated in the pharmaceutical monitoring and treatment process for a case of severe systemic allergic reaction after using Wujia shenghua capsules during the postpartum period.They screened the medication used by the patient during hospitalization and evaluated the relationship between the allergic reaction and Wujia shenghua capsules,as well as the possible causes of the reaction.RESULTS&CONCLUSIONS The relationship between severe systemic allergic reactions in the patient and Wujia shenghua capsules is evaluated as“likely related”,suggesting that patients with the allergic constitution should be vigilant when using Wujia shenghua capsules during the postpartum period,and pharmaceutical monitoring should be strengthened to avoid the simultaneous use of drugs with the same mechanism or potential interactions.

关 键 词：五加生化胶囊 全身性严重过敏反应 药学监护 药品不良反应 

分 类 号：R969.3[医药卫生—药理学]