血栓弹力图监测指导对急危重症输血患者血浆输注量、凝血功能及临床结局的影响  

The effect of thromboelastography monitoring on plasma infusion,coagulation function and clinical outcomes in acute and critical transfusion patients

作　　者：梁斌 程美玲[1] 颜悦新 Liang Bin;Cheng Meiling;Yan Yuexin(Bao'an District People's Hospital,Shenzhen,Guangdong 518101,China)

机构地区：[1]广东省深圳市宝安区人民医院,广东深圳518101

出　　处：《首都食品与医药》2024年第18期34-36,共3页Capital Food Medicine

摘　　要：目的探究血栓弹力图监测指导对急危重症输血患者血浆输注量、凝血功能及临床结局的影响.方法采用回顾性分析法,收集2020年2月-2023年7月在深圳市宝安区人民医院诊治的80例急危重症输血患者临床资料,根据监测指导方法的不同分为血栓弹力图监测组(研究组,47例)及常规凝血功能监测组(常规组,33例).观察两组患者血浆输注量情况;对比两组患者凝血功能水平[活化部分凝血酶原时间(APTT)、纤维蛋白原(FIB)、凝血酶原时间(PT)、凝血酶时间(TT)];分析两组患者临床结局变化.结果相较于常规组,研究组患者冷沉淀凝血因子、血浆及血小板输注量均显著减少(P<0.05).相较于常规组,研究组患者APTT、PT、TT时间明显缩短(P<0.05),FIB水平明显升高(P<0.05).与常规组对比,研究组住院时间、ICU停留时间及气管插管时间均显著缩短(P<0.05).结论血栓弹力图监测可减少急危重症输血患者血浆输注量,改善凝血功能及临床结局.Objective To investigate the effect of thromboelastography monitoring guidance on plasma transfusion volume,coagulation function and clinical outcomes of patients with acute and critical care blood transfusion.Methods A retrospective analysis was used to collect the clinical data of 80 patients with acute and critical blood transfusion treated in our hospital from February 2020 to July 2023,which were divided into a thromboelastography monitoring group(47 cases in the study group)and a routine group of routine coagulation function monitoring(33 cases in the routine group)according to the difference in the method of monitoring guidance.Observe the plasma transfusion volume of patients in the two groups.Compare the coagulation function levels[activated partial thromboplastin time(APTT),fibrinogen(FIB),prothrombin time(PT),prothrombin time(TT)]of patients in the two groups.Changes in clinical outcomes of patients in the two groups were analyzed.Results Compared with the routine group,the amount of cold-precipitated coagulation factors,plasma and platelet transfusions were significantly reduced in the study group(P<0.05).Compared with the routine group,patients in the study group had significantly shorter APTT,PT and TT times(P<0.05)and significantly higher FIB levels(P<0.05).Compared with the routine group,the hospitalization time,ICU stay time and tracheal intubation time were significantly shorter in the study group(P<0.05).Conclusion Thromboelastography monitoring can reduce the amount of plasma transfusion and improve coagulation function and clinical outcomes in patients with acute and critical transfusion.

关 键 词：血栓弹力图 急危重症输血 血浆输注量 凝血功能 临床结局 

分 类 号：R457[医药卫生—治疗学]