慢性阻塞性肺疾病合并肺结核肺通气功能障碍分析  

Analysis on chronic obstructive pulmonary disease combined with tuberculosis pulmonary ventilation dysfunction

作　　者：魏建华 焦晓 温静[2] 吕菊芬 高小娜 张冰美 WEI Jianhua;JIAO Xiao;WEN Jing;LYU Jufen;GAO Xiaona;ZHANG Bingmei(The Fourth People′s Hospital of Ningxia Hui Autonomous Region,Yinchuan 750021,China;Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏回族自治区第四人民医院,宁夏银川750021 [2]宁夏医科大学,宁夏银川750004

出　　处：《宁夏医学杂志》2024年第9期754-757,共4页Ningxia Medical Journal

基　　金：宁夏卫生健康系统科研课题(2022NWKY023)。

摘　　要：目的研究慢性阻塞性肺疾病(简称慢阻肺,COPD)合并初治病原学阳性肺结核(PTB)肺通气功能障碍特点。方法选择患者193例,根据患者临床诊断将其分为3组,A组(单纯慢阻肺组)60例,B组(单纯初治病原学阳性肺结核组)72例,C组(慢阻肺合并初治病原学阳性肺结核组)61例。3组患者住院期间均进行肺通气功能检查,对3组患者检查的各项肺功能指标进行统计学分析。结果在阻塞性肺通气功能障碍中,3组患者肺通气功能障碍的程度分级差异有统计学意义(P<0.05)。在限制性肺通气功能障碍中,C组均为中重度患者(100.00%),B组与C组患者肺通气功能障碍的程度分级差异有统计学意义(P<0.05)。3组患者中肺通气功能指标测定与支气管舒张试验测定结果B组最好。结论两病并发患者的肺功能表现为阻塞性肺通气功能障碍比例最高,肺通气功能最好的为单纯初治病原学阳性肺结核组。慢性阻塞性肺疾病合并初治病原学阳性肺结核患者肺功能检查是必要的,为临床诊疗提供良好的参考依据。Objective To study the characteristics of chronic obstructive pulmonary disease(COPD)combined with pulmonary ventilation dysfunction in primary pathogenetically positive tuberculosis(PTB).Methods A total of 193 patients were selected and divided into three groups according to their clinical diagnosis:60 patients in group A(simple chronic obstructive pulmonary group),72 patients in group B(simple primary pathogenetic positive pulmonary tuberculosis group),and 61 patients in group C(chronic obstructive pulmonary group combined with primary pathogenetic positive pulmonary tuberculosis group).Pulmonary ventilation function examination was carried out for the three groups during hospitalization,and the pulmonary function indexes examined in the three groups were analyzed statistically.Results In obstructive ventilation dysfunction,the difference in the degree of pulmonary ventilation dysfunction of the three groups of patients is statistically significant(P<0.05).In restricted ventilation dysfunction,group C were moderate and severe patients(100.00%),and the difference in the degree of pulmonary ventilation dysfunction between patients in group B and group C was statistically significant(P<0.05).The results of pulmonary ventilation function index and bronchial diastolic test of patients in the three groups were best in group B.Conclusion The highest proportion of obstructive ventilation dysfunction,and the best pulmonary ventilation function is in the simple primary treatment of pathogen-positive tuberculosis.Pulmonary function examination in patients with chronic obstructive pulmonary disease combined with primary pathogen-positive tuberculosis are necessary to provide a good reference for clinical diagnosis and treatment.

关 键 词：慢阻肺 初治 病原学 肺结核 

分 类 号：R562.25[医药卫生—呼吸系统]