泵机一体化的轴流式血泵模拟优化  

Simulation and optimization of integrated axial flow blood pump system

作　　者：何翊诚 邱胤轩 张亚[4] 崔佳鑫 鄂殿玉 HE Yicheng;QIU Yinxuan;ZHANG Ya;CUI Jiaxin;E Dianyu(Jiangxi Provincial Key Laboratory for Simulation and Modelling of Particulate Systems,Jiangxi University of Science and Technology,Nanchang 330013,China;International Institute for Innovation,Jiangxi University of Science and Technology,Nanchang 330013,China;School of Chemical Engineering,University of Queensland,Brisbane QLD 4067,Australia;Deparment of Otolaryngology Head and Neck Surgery,the Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,China)

机构地区：[1]江西理工大学江西省颗粒系统仿真与模拟重点实验室,江西南昌330013 [2]江西理工大学国际创新研究院,江西南昌330013 [3]昆士兰大学化工学院,昆士兰州布里斯班4067 [4]西安交通大学第二附属医院耳鼻咽喉头颈外科,陕西西安710004

出　　处：《中国医学物理学杂志》2024年第9期1152-1162,共11页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(52264042);江西省重大科技研发专项(20223AAG01009);江西省重点研发计划(20214BBG74005);江西省国际科技合作项目(20212BDH81001)。

摘　　要：针对现有的轴流式血泵存在一定的结构缺陷,导致性能不足和血液相容性差等问题,提出以一种泵机一体化的轴流式血泵为研究对象,利用计算流体力学方法,对其几何结构进行优化改进。同时研究不同运行参数对该血泵性能的影响,并与实验的数据进行比较,确定最佳的运行参数。本研究对该血泵的流场特性进行全面的分析,进一步揭示其内部的流动规律,并采用DPM方法模拟血液中红细胞的流动行为及其受剪切应力的情况,完成对该血泵的血液相容性的评估。研究表明,新型的血泵在扬程方面表现出良好的性能。在转速为9000r/min、流量为6.24L/min的最佳工况下,血泵的扬程比原结构提升16%,效率达到25%,能够满足大部分人的生理需求。此外血泵内大部分区域的压力梯度和速度梯度都比较均匀,内部流场情况比较稳定,能够有效避免溶血现象的发生。本研究优化改进的血泵能在确保高性能和良好的流场特性的同时具备较好的血液相容性,可为轴流式血泵的结构优化和改进提供重要的参考依据。Given that current axial flow blood pumps have certain structural defects,resulting in poor performance and inferior blood compatibility,an integrated axial flow blood pump is developed,and its geometry is optimized using computational fluid dynamics method.The study also investigates the effects of different operational parameters on the performance of the blood pump and compares with experimental data to determine the optimal conditions.Additionally,the flow patterns of the blood pump are comprehensively analyzed for further revealing the internal flow phenomena,and the behavior of red blood cells in the blood flow and their response to shear stress are simulated using discrete phase model to evaluate the blood compatibility of the blood pump.The study shows that the novel blood pump performed well in terms of head.Under the optimal condition with a rotational speed of 9000 r/min and a flow rate of 6.24 L/min,the blood pump improves the head by 16%as compared with the original structure,and reaches 25%efficiency,which can meet the physiological needs of most people.The pressure gradient and velocity gradient in most areas within the blood pump are smooth,and the internal flow patterns are generally stable,effectively avoiding the occurrence of hemolysis.The optimized blood pump can ensure high-level performance and favorable flow field characteristics while maintaining superior blood compatibility,which provides important reference for the structural optimization of axial flow blood pumps.

关 键 词：轴流式血泵 泵机一体化 结构优化 流场特性 血液相容性 

分 类 号：R318.11[医药卫生—生物医学工程]