哈蟆油现代研究进展及质量标志物预测分析  

Modern Research Progress and Quality Marker Prediction Analysis of Oviductus Ranae

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作  者:王海瑞 胡爽 李思奇 张巍[1] 白雪媛[1] WANG Hairui;HU Shuang;LI Siqi;ZHANG Wei;BAI Xueyuan(Institute of Traditional Chinese Medicine,Northeast Asia Institute of Traditional Chinese Medicine,Changchun University of Traditional Chinese Medicine,Changchun 130000,China;School of Traditional Chinese Medicine,Changchun University of Traditional Chinese Medicine,Changchun 130000,China)

机构地区:[1]长春中医药大学东北亚中医药研究院中药所,吉林长春130000 [2]长春中医药大学中医学院,吉林长春130000

出  处:《特产研究》2024年第5期124-134,共11页Special Wild Economic Animal and Plant Research

基  金:国家重点研发计划项目(2021YFD1600903);省级大学生创新创业项目(S202210199011X)。

摘  要:哈蟆油是我国吉林省道地药材,现代医学称其为“绿色软黄金”,被定为国家二级保护中药材,具有补肾益精、养阴润肺之功效,常用于病后体弱,神疲乏力,心悸失眠,盗汗,痨嗽咳血等病症的治疗。哈蟆油主要含有多糖、蛋白质、氨基酸、脂肪酸、甾体、类固醇、磷脂、核苷、维生素、矿物质元素等化学成分。本研究对哈蟆油的化学成分和药理作用进行归纳总结,同时结合质量标志物的概念理论,发现30余种可作为哈蟆油质量控制的潜在质量标志物,为进一步提升哈蟆油质量评价体系提供参考,助力哈蟆油高质量发展。Oviductus Ranae is a genuine medicinal herb in Jilin Province,China,known as"green soft gold"in modern medicine.It has been designated as a national second level protected Chinese medicinal herb and has the effects of tonifying the kidney,nourishing essence,nourishing yin and moistening the lungs.It is commonly used for the treatment of symptoms such as weakness,fatigue,palpitations,insomnia,night sweats,tuberculosis,cough and blood.It mainly contains chemical components such as polysaccharides,proteins,amino acids,fatty acids,steroids,phospholipids,nucleosides,vitamins,mineral elements,etc.This study summarized the chemical composition and pharmacological effects of Oviductus Ranae,and combined the concept theory of quality markers to discover more than 30 potential quality markers that can be used for quality control of Oviductus Ranae.This provides reference for further improving the economic efficiency and quality evaluation system of Oviductus Ranae production,and helps to promote the high-quality development of Oviductus Ranae.

关 键 词:哈蟆油 化学成分 药理作用 质量标志物 

分 类 号:R282[医药卫生—中药学] R284[医药卫生—中医学]

 

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