测定51种化妆品二甘醇残留量的气相色谱法  

Determination of Diethylene Glycol Residues in 51 Kinds of Cosmetics by Gas Chromatography

作　　者：林泽鹏 杜柏豪 李圣男 许鹏飞 许小冰 伍碧霞 Lin Zepeng;Du Bohao;Li Shengnan;Xu Pengfei;Xu Xiaobing;Wu Bixia(Guangzhou Fu′an Testing Technology Co.,Ltd.,Guangzhou 510555,China;Kangzheng Testing Service Co.,Ltd.,Guangzhou 510700,China;Guangdong Vocational College of Science and Trade,Guangzhou 510430,China)

机构地区：[1]广州辅安检测技术有限公司,广东广州510555 [2]康正检测服务股份有限公司,广东广州510700 [3]广东科贸职业学院,广东广州510430

出　　处：《山东化工》2024年第17期203-205,208,共4页Shandong Chemical Industry

摘　　要：以51种化妆品为分析对象,通过优化前处理、色谱条件、多次加标回收等因素测定了多种化妆品。样品经溶剂溶解、振荡、超声、过滤等前处理后,使用美国进口气相色谱仪带经氢火焰离子化检测器(FID)进行测定,使用极性毛细管色谱柱WAX(30 m×250μm×0.32μm)进行分离,以保留时间定性,外标法定量。标准品在质量浓度2.5~50μg·mL^(-1)范围,分析结果峰面积呈现良好的线性关系,相关系数R^(2)=0.9996;本方法选用低中高3个加标浓度:2.5,10,50.0μg/mL,各自平行加标n=6,得到平均回收率为94.8%~100%;以3倍信噪比、基线噪声为5.0 pA·s计算,检出限为2.24 mg·kg^(-1),定量限为6.72 mg·kg^(-1),RSD为1.94%~4.42%。在本方法的色谱条件下测定,可节约大量时间,并且污染小,检出限低,符合当下大批量化妆品的测定,可为测试化妆品提供有力的参考。Taking 51 kinds of cosmetics as the analysis object,many kinds of cosmetics were determined by optimizing pretreatment,chromatographic conditions,repeated standard recovery and other factors.After solvent dissolution,concussion,ultrasound and filtration,the samples were determined on the machine.The samples were determined by the imported American gas chromatograph with hydrogen flame ionization detector(FID).The samples were separated by polar capillary column WAX(30 m×250μm×0.32μm).The samples were qualitatively determined by retention time and quantified by external standard method.The peak area of the standard sample showed a good linear relationship in the concentration range of 2.5~50μg/mL,and the correlation coefficient was 0.9996.In this method,three low,medium and high concentrations were selected:2.5,10 and 50.0μg,respectively,and the average recovery was 94.8%~100%.When the signal-to-noise ratio is 3 times and the baseline noise is 5.0 pA·s,the detection limit is 2.24 mg·kg^(-1),and the quantitative limit is 6.72 mg·kg^(-1),RSD:1.94%~4.42%.The determination under the chromatographic condition of this method can save a lot of time,less pollution and low detection limit,which accords with the determination of large quantities of cosmetics at present,and can provide a powerful reference for testing cosmetics.

关 键 词：51种化妆品 二甘醇 气相色谱法 

分 类 号：O657.7[理学—分析化学]