苦参凝胶联合奥硝唑对耐药性滴虫性阴道炎患者临床症状消失时间、炎症反应指标的影响  

Effect of Matrine Gel Combined with Oronidazole on Disappearance Time of Clinical Symptoms and Index of Inflammatory Response in Patients with Resistant Trichomonas Vaginitis

作　　者：邓蜓蜓 DENG Tingting(Qianxinan State Hospital of Traditional Chinese Medicine,Xingyi 562400,China)

机构地区：[1]黔西南州中医医院,贵州兴义562400

出　　处：《中外医学研究》2024年第27期129-132,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨苦参凝胶结合奥硝唑对耐药性滴虫性阴道炎患者临床症状消失时间和炎症反应指标的影响。方法:选取2022年9月—2023年8月黔西南州中医医院收治的80例患有耐药性滴虫性阴道炎的患者作为研究对象,随机分为A组和B组,每组各40例。A组接受苦参凝胶和奥硝唑联合治疗,B组接受传统治疗,即奥硝唑单独治疗。比较两组临床症状消失时间、炎症反应指标情况。结果:治疗后,A组临床常见症状消失时间短于B组,差异有统计学意义(P<0.05)。治疗后,A组白细胞介素-8(IL-8)、白细胞介素-13(IL-13)水平低于对照组,差异有统计学意义(P<0.05)。结论:苦参凝胶结合奥硝唑联合治疗耐药性滴虫性阴道炎患者疗效显著,临床症状消失时间缩短,炎症反应得到有效控制。Objective:To explore the effect of Sophora flavescens gel combined with ornidazole on the disappearance time of clinical symptoms and inflammatory response indexes in patients with drug-resistant trichomonal vaginitis.Method:80 patients with drug-resistant trichomonal vaginitis admitted to Qianxinan Traditional Chinese Medicine Hospital from September 2022 to August 2023 were selected as the study objects and randomly divided into group A and group B,with 40 cases in each group.The patients of group A received the combined treatment of Matrine gel and ornidazole,while the patients of group B received traditional treatment-ornidazole alone.The disappearance time of clinical symptoms and inflammatory reaction indexes were compared between the two groups.Result:After treatment,the disappearance time of common clinical symptoms in group A was shorter than that in group B,and the difference was statistically significant(P<0.05).After treatment,Interleukin-8(IL-8)and Interleukin-13(IL-13)levels in group A were lower than those in control group,and the difference was statistically significant(P<0.05).Conclusion:Matrine gel combined with ornidazole is effective in the treatment of patients with resistant trichomoniasis vaginitis,the time of clinical symptoms disappearing is shortened,and the inflammatory reaction is effectively controlled.

关 键 词：苦参凝胶 耐药性 滴虫性阴道炎 联合用药 

分 类 号：R711.31[医药卫生—妇产科学]