酸枣仁的化学成分、药理作用和临床应用研究进展  

Research progress on the chemical composition,pharmacological action,and clinical application of Ziziphi spinosae semen

作　　者：曲彤 耿飞飞 李宁 鲁文静[1] 任慧[1] 崔小敏[1] 胡静 梁超 陈志永 张红[1] QU Tong;GENG Feifei;LI Ning;LU Wenjing;REN Hui;CUI Xiaomin;HU Jing;LIANG Chao;CHEN Zhiyong;ZHANG Hong(Shaanxi Academy of Traditional Chinese Medicine,Xi'an 710003,China;College of Pharmacy,Shaanxi University of Chinese Medicine,Xianyang 712046,Shaanxi Province,China)

机构地区：[1]陕西省中医药研究院,西安710003 [2]陕西中医药大学药学院,陕西咸阳712046

出　　处：《药学前沿》2024年第9期98-108,共11页China Pharmacist

基　　金：陕西省中医药管理局中医药全省性专款专项项目(2021-QYZL-01);“陕西省中医药管理局双链融合”中青年科研创新团队项目(2022-SLRH-YQ-003);陕西省中医药管理局“医研校企”中医药传承创新平台(中医药创新药物/器械“研发-转化-推广”平台)项目。

摘　　要：酸枣仁主要含有皂苷类、黄酮类、生物碱类、脂肪酸类等成分,具有镇静催眠、抗焦虑、抗抑郁、保护神经、保护心脑血管、保肝、抗氧化等多种活性,广泛应用于医药、食品、保健食品等领域。本文通过查阅文献,系统整理归纳了酸枣仁的化学成分、药理作用及临床应用,以期为酸枣仁资源的可持续开发和合理使用提供理论指导。Ziziphi spinosae semen mainly contains contents of saponins,flavonoids,alkaloids and aliphatic acids.Meanwhile,it has a variety of activities such as sedative-hypnotic,anti-anxiety,anti-depression,nerve protection,cardiovascular and cerebrovascular protection,liver protection,and antioxidant,which is widely used in medicine,food,health food and other fields.The chemical constituents,pharmacological action and clinical application of Ziziphi spinosae semen were systematically summarized in this paper by reviewing the literature,in order to provide theoretical guidance for the sustainable development of the resources and the rational use of Ziziphi spinosae semen.

关 键 词：酸枣仁 化学成分 药理作用 临床研究 皂苷 黄酮 生物碱 脂肪酸 

分 类 号：R285.6[医药卫生—中药学]