生物活性测定法在中药质量控制应用中的研究进展  

Research progress in the application of biological activity assay in the quality control of traditional Chinese medicine

作　　者：于思思 温苗 赵剑[1] 吴彦霖[2] YU Sisi;WEN Miao;ZHAO Jian;WU Yanlin(School of Life Sciences and Biopharmaceutical,Shenyang Pharmaceutical University,Shenyang 117004,China;National Institutes for Food and Drug Control,Beijing 102629,China;School of Pharmacy,China Pharmaceutical University,Nanjing 210009,China)

机构地区：[1]沈阳药科大学生命科学与生物制药学院,沈阳117004 [2]中国食品药品检定研究院,北京102629 [3]中国药科大学药学院,南京210009

出　　处：《药学前沿》2024年第9期170-180,共11页China Pharmacist

摘　　要：生物活性测定法可以有效保障中药的有效性和安全性,在中药质量检测中有良好的应用前景,同时可以和其他质量检测方法联合应用,建立多元化的中药质量控制模式。但生物活性测定法也存在一定的不足,面临许多的挑战,需要进一步的探索和发展。本文在介绍生物活性测定法基本内容的基础上,通过查找和阅读国内外相关文献,讨论生物活性测定法相较于化学分析方法和传统感官评价方法在中药质量检测中的优势及应用,以探讨生物活性测定法在中药质量控制中的应用及研究进展。Biological activity assay can effectively guarantee the effectiveness and safety of traditional Chinese medicine,has a good application prospect in the quality detection of traditional Chinese medicine,and can be combined with other quality detection methods to establish a diversified quality control model of traditional Chinese medicine.However,there are also some shortcomings in the biological activity assay,which faces many challenges and needs further exploration and development.Based on the introduction of the basic contents of biological activity assay,the advantages and applications of biological activity assay compared with chemical analysis and traditional sensory evaluation methods in the quality detection of traditional Chinese medicine were discussed through searching and reading domestic and foreign papers in this article,in order to discuss the application and research progress of biological activity assay in the quality control of traditional Chinese medicine.

关 键 词：中药 生物活性测定 质量控制 生物评价 化学评价 研究进展 

分 类 号：R284.1[医药卫生—中药学]