右美托咪定静脉泵注复合七氟醚吸入麻醉在子宫肌瘤手术患者中的应用效果  

Effect of intravenous injection of dexmedetomidine combined with sevoflurane inhalation anesthesia in patients undergoing uterine fibroid surgery

作　　者：杨艳 YANG Yan(Department of Anesthesiology,Ruijin Maternal and Child Health Hospital,Ruijin 342500,China)

机构地区：[1]瑞金市妇幼保健院麻醉科,342500

出　　处：《中国实用医药》2024年第19期127-130,共4页China Practical Medicine

基　　金：江西省卫生健康委科技计划(项目编号:SKJP220228436)项目名称:右美托咪定静脉泵注复合七氟醚吸入麻醉在子宫肌瘤手术患者中的应用效果。

摘　　要：目的 观察右美托咪定静脉泵注复合七氟醚吸入麻醉应用于子宫肌瘤手术患者中的临床效果。方法 筛选子宫肌瘤手术患者68例,以随机数字表法划分为观察组与对照组进行对照研究,各34例。对照组患者给予生理盐水静脉泵注复合七氟醚吸入麻醉处理,观察组患者则采用右美托咪定静脉泵注复合七氟醚吸入麻醉处理。对比两组麻醉效果(完全清醒后疼痛程度、复苏期躁动程度及麻醉不良反应发生情况),麻醉实施前后应激指标(心率、收缩压、舒张压),手术指标(术后自主呼吸恢复时间、术后拔管时间、术后苏醒时间、术后首次下床时间、住院时间)及麻醉满意度。结果 观察组患者术后完全清醒后疼痛程度评分(3.2±0.6)分、复苏期躁动程度评分(1.6±0.5)分、麻醉不良反应发生率2.9%均低于对照组的(4.5±0.8)分、(2.0±0.7)分、17.6%,两组数据对比差值有统计学意义(P<0.05)。麻醉实施前两组心率和血压指标对比无明显差异(P>0.05);麻醉实施后观察组患者的心率(83.3±1.7)次/min、收缩压(128.3±1.8)mm Hg(1 mm Hg=0.133 kPa)、舒张压(95.4±1.5)mm Hg均低于对照组的(95.5±1.9)次/min、(132.8±2.3)mm Hg、(101.3±1.6)mm Hg,两组数据对比差值有统计学意义(P<0.05)。观察组患者术后自主呼吸恢复时间(13.5±1.5)min、术后拔管时间(3.1±0.8)d、术后苏醒时间(10.4±1.4)min、术后首次下床活动时间(20.6±1.2)h、住院时间(5.8±0.8)d均短于对照组的(17.8±1.8)min、(4.5±1.0)d、(15.6±1.6)min、(24.3±1.6)h、(7.6±1.0)d,两组数据对比差值有统计学意义(P<0.05)。观察组患者麻醉满意度为97.1%,高于对照组的82.4%,两组数据结果对比差值有统计学意义(P<0.05)。结论 将右美托咪定静脉泵注复合七氟醚吸入麻醉应用于子宫肌瘤手术患者当中,可有效提高临床手术麻醉效果及安全性,减少患者术中应激反应发生,减轻患者术后疼痛程度,提高术后身体恢Objective To observe the clinical effect of intravenous injection of dexmedetomidine combined with sevoflurane inhalation anesthesia in patients undergoing uterine fibroid surgery.Methods 68 patients with uterine fibroid surgery were divided into an observation group and a control group for control study by random number table method,with 34 cases in each group.The control group was given intravenous injection of normal saline combined with sevoflurane inhalation anesthesia,while the observation group was given intravenous injection of dexmedetomidine combined with sevoflurane inhalation anesthesia.Both groups were compared in terms of anesthesia effect(pain after full awakening,agitation during resuscitation,and occurrence of adverse reactions to anesthesia),stress indicators(heart rate,systolic blood pressure,diastolic blood pressure)before and after anesthesia,surgical indicators(postoperative recovery time of spontaneous respiration,postoperative extubation time,postoperative recovery time,postoperative ambulation time and the length of hospital stay),and satisfaction with anesthesia.Results In the observation group,the pain score after full awakening was(3.2±0.6)points,the agitation score during resuscitation was(1.6±0.5)points,and the incidence of adverse reactions to anesthesia was 2.9%,which were lower than(4.5±0.8)points,(2.0±0.7)points,and 17.6%in the control group,and the difference between the two groups was statistically significant(P<0.05).There were no significant differences in heart rate and blood pressure between the two groups before anesthesia(P>0.05).After anesthesia,the observation group had heart rate of(83.3±1.7)beats/min,systolic blood pressure of(128.3±1.8)mm Hg(1 mm Hg=0.133 kPa),and diastolic blood pressure of(95.4±1.5)mm Hg,which were lower than(95.5±1.9)beats/min,(132.8±2.3)mm Hg,and(101.3±1.6)mm Hg in the control group,and the difference between the two groups was statistically significant(P<0.05).In the observation group,the postoperative recovery time of spontaneous resp

关 键 词：子宫肌瘤手术 右美托咪定 七氟醚 静脉泵注 吸入麻醉 

分 类 号：R614[医药卫生—麻醉学] R737.33[医药卫生—外科学]