探究布地奈德联合肾上腺素交替雾化吸入治疗小儿急性喉炎伴喉梗阻的临床效果  

The clinical effect of budesonide combined with epinephrine alternate aerosol inhalation in the treatment of acute laryngitis with laryngeal obstruction in children

作　　者：卢春 LU Chun(Ganzhou Maternal and Child Health Hospital,Ganzhou 341099,China)

机构地区：[1]赣州市妇幼保健院,341099

出　　处：《中国现代药物应用》2024年第18期104-106,共3页Chinese Journal of Modern Drug Application

摘　　要：目的 探究布地奈德联合肾上腺素交替雾化吸入治疗小儿急性喉炎伴喉梗阻的临床效果。方法 160例急性喉炎伴喉梗阻患儿,以随机数字表法分成对照组与试验组,每组80例。对照组接受布地奈德雾化吸入治疗,试验组患儿接受布地奈德联合肾上腺素交替雾化吸入治疗。对比两组治疗效果、临床症状消失时间以及不良反应发生情况。结果 与对照组(88.75%)对比,试验组总有效率(98.75%)更高(P<0.05)。治疗后,试验组喉鸣、犬吠样咳嗽、呼吸困难、声音嘶哑消失时间分别为(13.99±2.87)、(3.61±0.23)、(11.29±2.11)、(7.88±0.45)h,较对照组的(21.76±3.23)、(7.99±0.45)、(20.84±2.88)、(14.21±2.11)h更短(P<0.05)。治疗后,两组不良反应发生率对比无差异(P>0.05)。结论 小儿急性喉炎伴喉梗阻接受布地奈德+肾上腺素交替雾化吸入治疗后,患儿的临床症状明显改善,疗效显著,并具有较佳的治疗安全性,临床应用价值显著。Objective To explore the clinical effect of budesonide combined with epinephrine alternate aerosol inhalation in the treatment of acute laryngitis with laryngeal obstruction in children.Methods 160 children with acute laryngitis and laryngeal obstruction were divided into a control group and a test group using a random number table method,each with 80 cases.The control group received budesonide aerosol inhalation treatment,and the test group received budesonide combined with epinephrine alternate aerosol inhalation treatment.The treatment effect,disappearance time of clinical symptoms,and occurrence of adverse reactions were compared between the two groups.Results Compared with the control group(88.75%),the total effective rate(98.75%)was higher in the test group(P<0.05).After treatment,the disappearance time of laryngeal tinnitus,barking cough,dyspnea and hoarseness in children in the test group were(13.99±2.87),(3.61±0.23),(11.29±2.11)and(7.88±0.45)h,which were shorter than(21.76±3.23),(7.99±0.45),(20.84±2.88)and(14.21±2.11)h in the control group(P<0.05).After treatment,there was no difference in the comparison of the incidence of adverse reactions between the two groups(P>0.05).Conclusion Alternating aerosol inhalation of budesonide and epinephrine has significant clinical effect has significant efficacy on children with acute laryngitis and laryngeal obstruction,which can effectively improve the clinical symptoms of patients with better treatment safety,and has significant clinical application value.

关 键 词：布地奈德 肾上腺素 雾化吸入 小儿急性喉炎 喉梗阻 

分 类 号：R767.1[医药卫生—耳鼻咽喉科]