Epidemic Characteristics and Spatio-Temporal Patterns of HFRS in Qingdao City,China,2010-2022  

作　　者：Ying Li Runze Lu Liyan Dong Litao Sun Zongyi Zhang Yating Zhao Qing Duan Lijie Zhang Fachun Jiang Jing Jia Huilai Ma 

机构地区：[1]Chinese Field Epidemiology Training Program,Chinese Center for Disease Control and Prevention,Beijing 100050,China [2]National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China [3]Qingdao Municipal Center for Disease Control and Prevention,Qingdao 266024,Shandong,China [4]Jiaozhou Center for Disease Control and Prevention,Qingdao 266399,Shandong,China [5]Institute for Infectious Disease Control and Prevention,Shandong Center for Disease Control and Prevention,Jinan 250013,Shandong,China [6]Office of Epidemiology(Technical Guidance Office for Patriotic Health Work),Chinese Center for Disease Control and Prevention,Beijing 102206,China

出　　处：《Biomedical and Environmental Sciences》2024年第9期1015-1029,共15页生物医学与环境科学（英文版）

基　　金：supported by the Chinese Field Epidemiology Training Program,the Research and Development of Standards and Standardization of Nomenclature in the Field of Public Health-Research Project on the Development of the Disciplines of Public Health and Preventive Medicine[242402];the Shandong Medical and Health Science and Technology Development Plan[202112050731].

摘　　要：Objective This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome(HFRS)in Qingdao City,China.Methods Information was collected on HFRS cases in Qingdao City from 2010 to 2022.Descriptive epidemiologic,seasonal decomposition,spatial autocorrelation,and spatio-temporal cluster analyses were performed.Results A total of 2,220 patients with HFRS were reported over the study period,with an average annual incidence of 1.89/100,000 and a case fatality rate of 2.52%.The male:female ratio was 2.8:1.75.3%of patients were aged between 16 and 60 years old,75.3%of patients were farmers,and 11.6%had both“three red”and“three pain”symptoms.The HFRS epidemic showed two-peak seasonality:the primary fall-winter peak and the minor spring peak.The HFRS epidemic presented highly spatially heterogeneous,street/township-level hot spots that were mostly distributed in Huangdao,Pingdu,and Jiaozhou.The spatio-temporal cluster analysis revealed three cluster areas in Qingdao City that were located in the south of Huangdao District during the fall-winter peak.Conclusion The distribution of HFRS in Qingdao exhibited periodic,seasonal,and regional characteristics,with high spatial clustering heterogeneity.The typical symptoms of“three red”and“three pain”in patients with HFRS were not obvious.

关 键 词：Hemorrhagic fever with renal syndrome Epidemic characteristics Spatio-temporal distribution 

分 类 号：R512.8[医药卫生—内科学] R181.3[医药卫生—临床医学]