从“虚、滞、郁、瘀”病机理论探讨慢性萎缩性胃炎癌前病变微观辨治  

Microscopic syndrome differentiation and treatment of precancerous lesions of chronic atrophic gastritis based on the pathogenesis theory of “deficiency, stagnation, depression, and stasis”

作　　者：班彦然 方霜霜 王琳 卿香丽 白薇 杨洋[1] 魏玮[1] BAN Yanran;FANG Shuangshuang;WANG Lin;QING Xiangli;BAI Wei;YANG Yang;WEI Wei(Department of Spleen and Stomach Diseases(Digestion),Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102,China;Graduate School,Beijing University of Chinese Medicine,Beijing 100029)

机构地区：[1]中国中医科学院望京医院脾胃病科,北京100102 [2]北京中医药大学研究生院,北京100029

出　　处：《北京中医药》2024年第9期990-995,共6页Beijing Journal of Traditional Chinese Medicine

基　　金：中医药防治消化道癌前疾病传承与创新团队项目(ZYYCXTD-C-202210);中医药传承与创新“百千万”人才工程(岐黄工程)岐黄学者项目(GJZYY-2019-QHXZ);中国中医科学院望京医院自主选题专项课题(WJYY-ZZXT-2023-15)

摘　　要：魏玮教授认为“虚、滞、郁、瘀”是慢性萎缩性胃炎癌前病变发生发展的核心病机,本病的发病主要与脾胃虚损、阻滞不通、情志郁结、脉络瘀阻等因素有关,立足辨证论治,广泛汲取和采纳现代科学技术手段,结合“虚、滞、郁、瘀”核心病机及其物质基础、胃镜检查结果、病理检查结果等,从宏观与微观结合辨治等多角度系统探索慢性萎缩性胃炎癌前病变的物质基础与中医微观辨证的关系,实现中医药客观化、标准化的诊治策略,为本病的病机理论阐释与临床精准辨治提供参考。Professor WEI Wei believes that“deficiency,stagnation,depression,and stasis”are the core pathogenesis of the occurrence and development of precancerous lesions of chronic atrophic gastritis.The onset of this disease is mainly related to factors such as spleen and stomach deficiency,obstruction,emotional depression,and collateral stasis.Based on syndrome differentiation and treatment,modern scientific and technological methods are widely absorbed and adopted.By integrating the core pathogenesis of“deficiency,stagnation,depression,and stasis”with its material basis,gastroscopy results,and pathological findings,a systematic exploration of the relationship between the material basis of precancerous lesions of chronic atrophic gastritis and the microscopic syndrome differentiation of traditional Chinese medicine(TCM)is conducted from multiple perspectives,combining both macro and micro approaches.It enables the realization of an objective and standardized diagnosis and treatment strategy in TCM,providing a reference for the theoretical interpretation of the pathogenesis and precise clinical syndrome differentiation and treatment of this disease.

关 键 词：虚 滞 郁 瘀 慢性萎缩性胃炎 胃癌前病变 微观辨证 宏观辨证 

分 类 号：R259[医药卫生—中西医结合]