自制中药漱口液治疗胃火炽盛型牙周炎临床观察  

Clinical observation on self-made Chinese medicine gargle in treatment of periodontitis with intense stomach fire syndrome

作　　者：杨薇[1] 刘晶 龙峻标[1] YANG Wei;LIU Jing;LONG Junbiao(Guang'anmen Hospital South District,China Academy of Chinese Medical Sciences,Beijing 102618,China)

机构地区：[1]中国中医科学院广安门医院南区,北京102618

出　　处：《北京中医药》2024年第9期1024-1027,共4页Beijing Journal of Traditional Chinese Medicine

基　　金：中国中医科学院广安门医院南区院级科研基金课题(Y2023-11)。

摘　　要：目的观察自制中药含漱液治疗胃火炽盛型牙周炎的临床疗效。方法选取2023年1月—2024年1月在中国中医科学院广安门医院南区口腔科就诊的胃火炽盛型慢性牙周炎患者100例,使用随机数字法将患者分为2组。2组患者均接受口腔卫生宣教和牙周基础治疗,观察组用自制中药含漱液含漱2 min,25~30 mL/次,3次/d,对照组用生理盐水含漱,方法同观察组。2组均连续漱口2周。对比2组治疗前后龈沟液中白细胞介素1β(IL-1β)、肿瘤坏死因子α(TNF-α)、超敏C反应蛋白(hs-CRP)、牙龈指数(GI)、龈沟出血指数(SBI)、牙周袋探诊深度(PD)、中医证候积分。结果治疗后,2组龈沟液中CRP、IL-1β、TNF-α、GI、SBI、PD及牙龈肿痛、出血、口臭、便秘评分均低于治疗前(P<0.05),且观察组低于对照组(P<0.05)。结论自制中药含漱液可减轻胃火炽盛型牙周炎患者牙周炎症反应,改善牙周状态及临床症状。Objective To observe the clinical efficacy of a self-made Chinese medicine gargle in the treatment of periodontitis with intense stomach fire syndrome.Methods A total of 100 patients with chronic periodontitis of intense stomach fire syndrome,treated at the Department of Stomatology,Guang'anmen Hospital South District of the China Academy of Chinese Medical Sciences from March 2023 to March 2024 were enrolled and randomly divided into two groups using a random number method.Both groups received oral hygiene education and basic periodontal treatment.The observation group gargled with a self-made Chinese medicine solution for 2 min,25–30 mL per use,3 times a day.The control group gargled with 0.9%saline solution following the same method as the observation group.Both groups continued gargling for 2 weeks.The levels of interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α),high-sensitivity C-reactive protein(hs-CRP),gingival index(GI),sulcus bleeding index(SBI),and traditional Chinese medicine(TCM)syndrome scores were compared between the two groups before and after treatment.Results After treatment,the levels of CRP,IL-1β,TNF-α,GI,SBI in gingival crevicular fluid,and the scores for gingival swelling,bleeding,halitosis,and constipation in both groups were lower than those before treatment(P<0.05),and the observation group showed significantly lower levels than the control group(P<0.05).Conclusion The self-made Chinese medicine gargle can reduce the periodontal inflammatory response in patients with periodontitis of intense stomach fire syndrome and improve periodontal status and clinical symptoms.

关 键 词：牙周炎 中药漱口液 胃火炽盛型 

分 类 号：R276.8[医药卫生—中医五官科学]