左氧氟沙星联合头孢唑肟治疗老年肺炎的疗效及对患者肺功能的影响  

The Efficacy of Levofloxacin Combined with Cefozoxime in the Treatment of Pneumonia in the Elderly and the Effects on Patients Lung Function

作　　者：谷志永 GU Zhiyong(Department of Pulmonary Disease,Lianshui Hospital of Traditional Chinese Medicine,Lianshui 223400,Jiangsu,China)

机构地区：[1]涟水县中医院肺病科,江苏涟水223400

出　　处：《系统医学》2024年第15期81-83,87,共4页Systems Medicine

摘　　要：目的 探讨左氧氟沙星联合头孢唑肟治疗老年肺炎的疗效。方法 非随机选取涟水县中医院于2022年8月—2023年8月收治的68例老年肺炎患者为研究对象,按不同的治疗方法分组。对照组(n=34)采用头孢唑肟治疗,观察组(n=34)采用头孢唑肟联合左氧氟沙星治疗。比较两组疗效、症状改善时间、肺功能与不良反应发生率。结果 观察组治疗总有效率为97.06%(33/34),高于对照组的79.41%(27/34),差异有统计学意义(χ^(2)=5.100,P<0.05)。观察组症状改善时间短于对照组,肺功能指标水平优于对照组,差异有统计学意义(P均<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 左氧氟沙星联合头孢唑肟治疗老年肺炎的疗效显著,可改善患者症状及肺功能,不良反应少。Objective To investigate the efficacy of levofloxacin combined with cefazoxime in the treatment of pneu-monia in the elderly.Methods Sixty-eight cases of elderly patients with pneumonia admitted to Lianshui County Hos-pital of Traditional Chinese Medicine from August 2022 to August 2023 were non-randomly selected as study subjects and grouped according to different treatment methods.The control group(n=34)was treated with cefozoxime,and the observation group(n=34)was treated with cefozoxime combined with levofloxacin.The efficacy,symptom improve-ment,lung function and incidence of adverse reactions were compared between the two groups.Results The total effec-tive rate of the observation group was 97.06%(33/34),which was higher than 79.41%(27/34)of the control group,and the difference was statistically significant(χ^(2)=5.100,P<0.05).The observation group′s symptom improvement time was shorter than that of the control group,and the level of lung function indexes were better than that of the control group,and the differences were statistically significant(all P<0.05).There was no statistically significant difference in incidence of adverse reactions between the two groups(P>0.05).Conclusion The efficacy of levofloxacin combined with cefozoxime in the treatment of pneumonia in the elderly is remarkable,improving patients′symptoms and lung function with few adverse effects.

关 键 词：左氧氟沙星 头孢唑肟 老年肺炎 临床疗效 肺功能 不良反应 

分 类 号：R563.1[医药卫生—呼吸系统]