外周血涂片联合骨髓细胞形态学检查对白血病诊断的临床价值研究  

Clinical Value of Peripheral Blood Smear Combined with Bone Marrow Cell Morphology Examination in the Diagnosis of Hematological Diseases

作　　者：岑志炜 练小芬 李小玲 陈志强 何经纬 CEN Zhiwei;LIAN Xiaofen;LI Xiaoling;CHEN Zhiqiang;HE Jingwei(Laboratory Department,Xinxing County People's Hospital of Yunfu,Yunfu 527400,Guangdong,China)

机构地区：[1]云浮市新兴县人民医院检验科,广东云浮527400

出　　处：《系统医学》2024年第15期101-104,共4页Systems Medicine

基　　金：云浮市医学科学技术研究立项(2021B142)。

摘　　要：目的 探讨外周血涂片联合骨髓细胞形态学检查对白血病诊断的临床价值。方法 目的抽样法选取2019年1月-2022年1月云浮市新兴县人民医院收治的57例疑似白血病患者为研究对象。所有患者均接受了外周血涂片检查、骨髓细胞形态学检查,金标准为骨髓活检。比较两种检查方法的诊断效能。结果 外周血涂片检查、骨髓细胞形态学检查、联合检查诊断白血病的曲线下面积分别为0.782、0.853、0.911,外周血涂片检查、骨髓细胞形态学检查、联合检查的灵敏度分别为85.37%(35/41)、87.80%(36/41)、97.56%(40/41),特异度分别为31.25%(5/16)、75.00%(12/16)、87.50%(14/16)。结论 对于血液疾病患者,采用外周血涂片联合骨髓细胞形态学检查有助于提高诊断效能,有较高应用价值。Objective To investigate the clinical value of peripheral blood smear combined with bone marrow cell mor-phological examination in the diagnosis of leukemia.Methods Fifty-seven suspected leukemia patients admitted to Xinxing County People′s Hospital in Yunfu City from January 2019 to January 2022 were selected as the research ob-jects by target sampling method.All patients underwent peripheral blood smear examination and bone marrow cell morphology examination,with the gold standard being bone marrow biopsy.Compare the diagnostic efficacy of two ex-amination methods.Results The area under the curve for diagnosing leukemia by peripheral blood smear examination,bone marrow cell morphology examination,and combined examination was 0.782,0.853,and 0.911,respectively.The sensitivity of peripheral blood smear examination,bone marrow cell morphology examination,and combined examina-tion was 85.37%(35/41),87.80%(36/41),and 97.56%(40/41),respectively,and the specificity was 31.25%(5/16),75.00%(12/16),and 87.50%(14/16).Conclusion For patients with hematological diseases,the combination of periph-eral blood smear and bone marrow cell morphology examination can improve diagnostic efficiency and has high appli-cation value.

关 键 词：外周血涂片 骨髓细胞形态学 血液疾病诊断 临床价值 

分 类 号：R446.11[医药卫生—诊断学]