地诺前列酮栓在足月妊娠孕妇促宫颈成熟与试产的作用分析  

Effect of Dinoprostol Suppository in Promoting Cervical Maturation and Trial Labor in Full-term Pregnant Women

作　　者：孙艳丽 SUN Yanli(Department of Obstetrics and Gynecology,Xuzhou Heping Maternity Hospital,Xuzhou 221000,Jiangsu,China)

机构地区：[1]徐州和平妇产医院妇产科,江苏徐州221000

出　　处：《系统医学》2024年第15期152-155,共4页Systems Medicine

摘　　要：目的 分析地诺前列酮栓在足月妊娠孕妇促宫颈成熟与试产中的作用。方法 目的选取2020年1月-2023年10月在徐州和平妇产医院接受试产的足月妊娠孕妇76例,以治疗方法不同分为两组,以米索前列醇治疗的38例纳入对照组,以地诺前列酮栓治疗的38例纳入观察组。对比两组宫颈成熟度(Bishop评分)、试产效果、试产成功率与不良反应。结果 治疗后,观察组宫颈Bishop评分较对照组高,观察组24 h内分娩率较对照组高,观察组用药至临产平均时间较对照组短,差异有统计学意义(P均<0.05)。观察组试产成功率为94.74%(36/38),较对照组76.32%(29/38)高,差异有统计学意义(χ^(2)=5.208,P<0.05)。观察组不良反应发生率较对照组低,差异有统计学意义(P均<0.05)。结论 利用地诺前列酮栓可以进一步加快足月妊娠孕妇促宫颈成熟,提高宫颈Bishop评分,对于提高产妇试产成功率有积极作用,且不良反应较少,具有临床价值。Objective To analyze the effect of Dinoprostol suppository in promoting cervical maturation and trial labor in full-term pregnant women.Methods 76 full-term pregnant women who received trial labor in Xuzhou Heping Ma-ternity Hospital from January 2020 to October 2023 were objectively selected,and divided into two groups by different treatment.38 cases treated with misoprostol were included in the control group and 38 cases treated with dinoprostol suppositing were included in the observation group.Compare the cervical maturity(Bishop score),trial labor effect,trial labor success rate and adverse reactions between two groups.Results After treatment,the cervical Bishop score of the observation group was higher than that of the control group;the delivery rate within 24 h in the observation group was higher than that in the control group,and the average time from medication to labor was shorter than that in the control group,the difference was statistically significant(all P<0.05).The success rate of trial production in the ob-servation group was 94.74%(36/38),higher than 76.32%(29/38)in control group,the difference was statistically sig-nificant(χ^(2)=5.208,P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion The use of Dinoprostol suppository can further accelerate cervical maturation in full-term pregnant women and improve cervical Bishop score,which has a positive effect on improving the success rate of trial labor,and has less adverse reactions,and has clinical value.

关 键 词：地诺前列酮栓 足月妊娠 促宫颈成熟 试产 

分 类 号：R719[医药卫生—妇产科学]