三手烟暴露对儿童手术麻醉相关并发症及术后转归的影响  

Effect of Third-hand Smoke Exposure on Anesthesia Related Complications and Postoperative Outcomes in Children

作　　者：曾亮华 詹小璇 赖丽妃 林绮华 Zeng Lianghua(Shenzhen Qianhai Shekou Free Trade Zone Hospital,Shenzhen 518000)

机构地区：[1]深圳市前海蛇口自贸区医院,广东深圳518000 [2]中山大学附属第八医院,广东广州510000 [3]中山大学附属第七医院,广东广州510000 [4]深圳市妇幼保健院,广东深圳518000

出　　处：《黑龙江医药》2024年第5期1076-1079,共4页Heilongjiang Medicine journal

基　　金：深圳市南山区科技计划项目(课题编号:2022108)。

摘　　要：目的:探究三手烟暴露对儿童手术麻醉相关并发症及术后转归的影响。方法:收集深圳市前海蛇口自贸区医院在2021年10月—2024年2月期间接受气管插管全身麻醉手术治疗的患儿495例,按同住人是否吸烟和(或)在家里吸烟等情况分为3组,即无暴露组(N组)182例、THS暴露组(T组)159例、SHS与THS暴露组(ST组)154例。收集患者术后插管及相关并发症情况,术后返回病房情况,出院后15天随访情况,分析比较3组麻醉相关并发症发生率,住院时间以及术后转归情况。结果:3组麻醉相关并发症发生率、术后镇痛使用率、出院后再次就诊率及二次住院率比较,无统计学差异(P>0.05)。3组术后呼吸道症状发生率、麻醉时间、手术时间、住院时间、出院后呼吸道症状发生率比较,有统计学差异(P<0.05);且T组术后呼吸道症状发生率均较N组、ST组高(P<0.05);ST组麻醉时长、手术时间、住院时间均较N组、T组长(P<0.05);T组手术时间、住院时间均较N组长(P<0.05);T组、ST组出院后呼吸道症状发生率均较N组高(P<0.05)。结论:接受气管插管全身麻醉手术治疗的患儿受三手烟暴露影响,虽术后出现呼吸道症状,但并未增加麻醉相关并发症发生率,而患儿在出院后仍有呼吸道症状发生,需引起重视。Objective:To explore the effects of third-hand smoke exposure on anesthesia related complications and postoperative outcomes in children.Methods:A total of 495 children who received tracheal intubation general anesthesia in Shenzhen Qianhai Snake mouth Free Trade Zone hospital from October 2021 to February 2024 were collected and divided into 3 groups according to whether their roommates smoked and/or smoked at home.No exposure group(N group)182 cases,TSH exposure group(T group)159 cases,SHS and TSH of exposed group(ST)in 154 cases.Postoperative intubation and related complications,postoperative return to the ward,and 15d follow-up after discharge were collected.The incidence rate of anesthesia related complications,length of stay and postoperative outcomes of the 3 groups were analyzed and compared.Results:There were no significant differences in the incidence of anesthesia-related complications,the rate of postoperative analgesia,the rate of re-visit after discharge and the rate of secondary hospitalization among the 3 groups(P>0.05).There were statistical differences in the incidence of postoperative respiratory symptoms,anesthesia time,operation time,hospital stay and post-discharge respiratory symptoms among the 3 groups(P<0.05).The incidence of postoperative respiratory symptoms in T group was higher than that in N group and ST group(P<0.05).The duration of anesthesia,operation and hospital stay in ST group were longer than those in N group and T group(P<0.05).The operation time and hospital stay in T group were longer than those in N group(P<0.05).The incidence of respiratory symptoms after discharge in T group and ST group was higher than that in N group(P<0.05).Conclusion:Children who received tracheal intubation under general anesthesia were affected by third-hand smoke exposure.Although respiratory symptoms appeared after surgery,the incidence of anesthesiation-related complications did not increase.However,respiratory symptoms still occurred after discharge,which should be paid attention to.

关 键 词：三手烟暴露 儿童 手术麻醉 并发症 术后转归 

分 类 号：R614[医药卫生—麻醉学]