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作 者:郭蓉 肖芳 GUO Rong;XIAO Fang(Xiangya School of Public Health,Central South University,Changsha,410006,China)
出 处:《环境化学》2024年第9期2897-2904,共8页Environmental Chemistry
基 金:国家自然科学基金(42277438);中南大学中央高校基本科研业务费专项资金(2021zzts0968,2022ZZTS0999,2023ZZTS0913)资助。
摘 要:近年来,微塑料因污染的广泛性引起全球关注,但人们在其健康损害方面的知识却非常匮乏.目前已经在世界各地的空气中检测到了多种类型的微塑料,且诸多证据显示微塑料可被机体吸入并在肺部沉积.而相对于肠道、肝脏等器官的广泛研究,微塑料对呼吸系统的影响却鲜有关注.本文从大气微塑料的环境行为、人群呼吸系统暴露情况、呼吸系统损害的流行病学研究、肺部损害的毒理学研究及相关机制等多个维度进行了全方位的综述探讨,以期为后续研究微塑料的呼吸系统健康效应提供一定的理论参考.In recent years,microplastics have attracted global attention due to the widespread pollution,but there is a paucity of knowledge regarding their health damage.Many types of microplastics have been detected in the air all over the world,and there is considerable evidence that they can be inhaled and deposited in the lungs.However,in contrast to the extensive research on other organs such as the intestine and liver,little attention has been paid to the effects of microplastics on the respiratory system.This paper presents a comprehensive review of the environmental behavior of atmospheric microplastics,exposure to the respiratory system in population,epidemiological research on respiratory damage,toxicological research on lung damage and related mechanisms,with a view to providing a theoretical reference for future research on the pulmonary health effects of microplastics.
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