2015-2022年威海市宫颈癌流行特征及疾病负担分析  

Analysis on epidemiological characteristics and disease burden of cervical cancer in Weihai city from 2015 to 2022

作　　者：曲文勇[1] 何丽萍[1] 周俊楠 QU Wen-yong;HE Li-ping;ZHOU Jun-nan(Operations Management Section,Weihai City Center for Disease Control and Prevention,Shandong 2642o0,Chi)

机构地区：[1]威海市疾病预防控制中心业务管理科,山东264200

出　　处：《预防医学论坛》2024年第6期450-453,457,共5页Preventive Medicine Tribune

摘　　要：目的了解2015-2022年威海市宫颈癌主要流行特征和疾病负担。方法利用2015-2022年威海市居民恶性肿瘤监测数据和同期人口资料,计算宫颈癌发病率、患病率、死亡率、伤残调整寿命年(DALY)率、过早死亡损失寿命年(YLL)率、伤残损失寿命年(YLD)率及相应的调整率。采用Joinpoint Regression Program 4.9.0.0软件计算率的年度变化百分比(APC),判断趋势走向,采用对数直线回归法对APC进行检验,分析宫颈癌主要流行特征及疾病负担变化情况。结果2015-2022年威海市宫颈癌粗发病率为14.91/10万~20.41/10万,调整率为10.05/10万~13.29/10万;粗患病率为32.10/10万~131.02/10万,调整率为21.68/10万~78.13/10万;粗死亡率为2.35/10万~4.93/10万,调整率为1.52/10万~2.94/10万,粗患病率、粗死亡率和调整患病率的上升差异有统计学意义(t值分别为10.454、2.586和8.770,P<0.05)。年龄组发病率总体以45~54岁组最高;年度年龄组发病率除35~44岁组外,均呈上升表现,其中25~34岁、55~64岁、75岁及以上年龄组发病率的上升有统计学意义(t值分别为3.181、4.574和3.935,P<0.05)。DALY率为0.45‰~0.78‰,YLL率为0.37‰~0.68‰,YLD率为0.08‰~0.10‰;年龄组DALY率总体以45~54岁组最高;25~34、55~64年龄组YLD率和75岁及以上年龄组的YLD率和YLL率呈上升趋势,差异有统计学意义(t值分别为2.650、4.360、2.721和4.204,P<0.05)。结论威海市宫颈癌年度发病率、死亡率、健康负担总体保持稳定,粗死亡率的上升与人口老龄化有关。年度不同年龄组的发病率、健康负担的趋势走向不一,发病年轻化趋势和高龄健康负担加重趋势明显。Objective To understand the main epidemiological characteristics and disease burden trends of cervical cancer in Weihai city.Methods Using the monitoring data of malignant tumors among residents and population data in Weihai city from 2015 to 2022,the incidence,prevalence,mortality,the premature death loss life years(YLL),the disability loss life years(YLD),annual disability adjusted life years(DALY),and corresponding adjustment rate of cervical cancer were calculated.The rate of the annual percentage change(APC)was calculated using the Joinpoint software,and the main epidemiological characteristics and changes in disease burden were analyzed.Results From 2015 to 2022,the crude incidence of cervical cancer in Weihai city fluctuated from 14.91/10~5 to 20.41/10~5,and the adjusted rate was from 10.0~5/10~5 to 13.29/10~5;the crude prevalence fluctuated from 32.10/10~5 to 131.02/10~5,and the adjusted rate was from 21.68/10~5 to 78.13/10~5;the crude mortality fluctuated from 2.35/10~5 to 4.93/10~5,and the adjusted rate was from 1.52/10~5 to 2.94/10~5.The increase of crude prevalence,crude mortality,and adjusted prevalence was statistically significant(t=10.454,2.586 and 8.770,P<0.05).The incidence of age group was the highest in the 45-54 year old group;Except for the 35-44 year old group,the annual age group incidence showed an upward trend,with statistically significant increases in the 25-34,55-64,75 and above(t=3.181,4.574 and 3.935,P<0.05).The DALY fluctuated from 0.45 to 0.78‰,the YLL fluctuated from 0.37 to 0.68‰,and YLD fluctuated from 0.08 to 0.10‰;the DALY rate was generally highest in the 45-54 year old group;the YLD rate of the 25-34 and 55-64 year old groups and the YLD rate and YLL rate of the 75 and above showed an upward trend with statistically significant differences(t=2.650,4.360,2.721 and 4.204,P<0.05).Conclusion The annual incidence,mortality and health burden of cervical cancer in Weihai city remained stable,and the increase of crude mortality was associated with ageing.Trends in morbidity a

关 键 词：宫颈癌 威海市 流行特征 疾病负担 

分 类 号：R737.33[医药卫生—肿瘤] R181.37[医药卫生—临床医学]