清新方防治新型冠状病毒感染临床研究  

Clinical Study of Qingxin Formula on Prevention and Treatment of Novel Coronavirus Infection

作　　者：王素英 朱龙[1,2] 邓亚平 陈淑娇 蔡晶 李灿东 WANG Su-ying;ZHU Long;DENG Ya-ping;CHEN Shujiao;CAI Jing;LI Can-dong(College of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou350122;Studio of National Famous TCM Physician L/Can-dong,Fuzhou350122;Preventive Treatment Department,The Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou350122;Geriatrics Department,The Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou350122)

机构地区：[1]福建中医药大学中医学院,福州350122 [2]全国名中医李灿东教授工作室,福州350122 [3]福建中医药大学附属第三人民医院治未病科,福州350122 [4]福建中医药大学附属第三人民医院老年病科,福州350122

出　　处：《中国中西医结合杂志》2024年第8期928-935,共8页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：福建中医药大学高层次人才科研启动基金项目(No.X2020005-人才)。

摘　　要：目的总结清新方在福州市新型冠状病毒感染防治中的疗效.方法纳入2022年12月30日-2023年2月28日就诊于福建中医药大学附属第三人民医院的1141例新冠感染患者,其中接受清新方治疗的患者525例(清新方治疗组)、常规化治疗的患者616例(常规治疗组).对患者进行中医状态辨识并予以相应药物治疗,收集患者一般资料、治疗前后症状及病程等结果进行统计分析.结果本研究新冠感染患者以青年女性偏多(P<0.05),其中清新方治疗组中有吸烟史[75例(14.29%)]和糖尿病史[39例(7.43%)]的人数多于常规治疗组(P<0.05).所有患者入院时以发热(70.20%)、咳嗽(65.99%)、乏力(53.55%)、怕冷(51.27%)和肌肉酸痛(49.96%)5个症状所占频率最多.与常规治疗比较,清新方治疗可显著改善新冠感染患者咳痰和流涕症状、缩短病程(P<0.01,P<0.05);即便新冠感染患者有吸烟史和糖尿病史,清新方对其防治仍有效果(P<0.05).结论清新方在福州市新冠感染的防治中表现出了明显的疗效,适用于新冠感染全周期、个性化动态防治.Objective To summarize the efficacy of Qingxin Formula in the prevention and treatment of novel coronavirus infection in Fuzhou City,China.Methods A total of 1141 COVID-19 patients who sought medical care at the Third People's Hospital affiliated to Fujian University of Traditional Chinese Medicine between December 30,2022,and February 28,2023 were included in this study.Among them,525 patients received treatment with the Qingxin Formula(Qingxin Formula treatment group),and 616 patients received conventional treatment(conventional treatment group).Patients received Chinese medicine status identification and corresponding drug treatments.General patient information,symptoms before and after treatment,and disease progression data were collected for statistical analysis.Results The general results of this study showed that more young women were infected with a novel coronavirus(P<0.05),and the number of patients with smoking history[75 cases(14.29%)]and diabetes history[39 cases(7.43%)]in the Qingxin treatment group was higher than that in the conventional treatment group(P<0.05).Fever(70.20%),cough(65.99%),fatigue(53.55%),chills(51.27%)and muscle aches(49.96%)were the most frequent symptoms in all patients.Compared with conventional treatment,Qingxin Formula could significantly improve the symptoms of sputum and runny nose;and shorten the course of disease in patients with novel coronavirus infection(P<0.01,P<0.05).Even if the novel coronavirus infected patients had a history of smoking and diabetes,Qingxin Formula still showed an effect of prevention and treatment(P<0.05).Conclusion The Qingxin Formula has shown significant therapeutic effects in the prevention and treatment of novel coronavirus infections in Fuzhou City,and is suitable for the whole-cycle of novel coronavirus infection and personalized dynamic prevention and treatment.

关 键 词：新型冠状病毒感染 清新方 状态辨识 全周期 个性化 中药 中西医结合 

分 类 号：R259[医药卫生—中西医结合]