传染性软疣样先天自愈性朗格汉斯细胞组织细胞增生症一例并文献复习  

Infectious soft wart like congenital self-healing Langerhans cell histiocytosis:a case report and literature review

作　　者：陈学超 王建文[1,2] 卢宪梅 杨青[1,2] CHEN Xuechao;WANG Jianwen;LU Xianmei;YANG Qing(Hospital for Skin Diseases,Shandong First Medical University,Jinan 250022,China;Shandong Provincial Institute of Dermatology and Venereology,Shandong Academy of Medical Sciences,Jinan 250022,China)

机构地区：[1]山东第一医科大学附属皮肤病医院,山东济南250022 [2]山东省皮肤病性病防治研究所,山东济南250022

出　　处：《中国麻风皮肤病杂志》2024年第11期799-801,共3页China Journal of Leprosy and Skin Diseases

基　　金：山东省医药卫生科技发展计划项目(编号:202004120639)。

摘　　要：先天自愈性朗格汉斯细胞组织细胞增生症是一种少见的新生儿疾病,初发年龄多为出生至9个月,皮损表现多样,多为丘疹、结节、丘疱疹,皮下结节等。本文报道一例3个月女性患儿,躯干、下肢散发粟粒大小丘疹,部分皮疹中央可见脐凹,部分皮疹顶部结痂。皮损组织病理及免疫组化染色符合朗格汉斯细胞组织细胞增生症。未予治疗,随访4个月皮疹消退,随访1年无新发皮疹。Congenital self-healing Langerhans cell histiocytosis is a rare disease in newborn.The onset age of the disease was mostly between birth and 9 months.The skin lesions were mostly papules,nodules,papuloherpes,subcutaneous nodules,etc.We report a three-month-old girl presented with sporadic miliary papules on the trunk and lower limbs,with the umbilical-fovea in the center or crusts on the top of papules.The features of pathological examination and immunohistochemical staining of the skin lesions were consistent with Langerhans cell histiocytosis.The patient received no treatment,the rash subsided after 4 months follow-up,and no new rash occurred after 1 year follow-up.

关 键 词：朗格汉斯组织细胞增生症 自愈性 先天性 

分 类 号：R722.1[医药卫生—儿科]