生物制剂治疗皮肤病过程中的矛盾性反应  

Update of paradoxical reactions during biological agents treatment for dematosis

作　　者：徐凡力 户茗珈 敖穗婷 刘红 张福仁[1,2] XU Fanli;HU Mingjia;AO Suiting;LIU Hong;ZHANG Furen(Hospital for Skin Diseases,Shandong First Medical University,Jinan 250022,China;Shandong Provincial Institute of Dermatology and Venereology,Shandong Academy of Medical Sciences,Jinan 250022,China)

机构地区：[1]山东第一医科大学附属皮肤病医院,山东济南250022 [2]山东省皮肤病性病防治研究所,山东济南250022

出　　处：《中国麻风皮肤病杂志》2024年第11期812-817,共6页China Journal of Leprosy and Skin Diseases

基　　金：山东省重点研发计划(重大科技创新工程)项目(编号:2021LCZX07)。

摘　　要：生物制剂在治疗皮肤病的过程中,可能会引发其他疾病或导致原有疾病的恶化,这种现象在临床上被称为矛盾性反应。已经有大量的矛盾反应被报道,如矛盾性银屑病、炎症性肠病、化脓性汗腺炎等。本文综述了生物制剂在治疗皮肤病过程中引起的各类矛盾反应。In the process of treating dermatosis,biological agents may cause other diseases or lead to the deterioration of existing diseases,this phenomenon is called the paradoxical reaction.A large number of paradoxical reactions have been reported.In this paper,we review the various paradoxical reactions caused by biological agents in the treatment of dematosis.

关 键 词：生物制剂 矛盾性反应 自身免疫性疾病 

分 类 号：R751.05[医药卫生—皮肤病学与性病学]