童年期创伤与静息态血压、心率及心血管疾病的相关性研究进展  

Research progress in the correlation between childhood trauma and resting blood pressure,resting heart rate,and cardiovascular disease

作　　者：刘快快 白美娜 黄凡凡 王学义[1] Liu Kuaikuai;Bai Meina;Huang Fanfan;Wang Xueyi(Mental Health Center,the First Hospital of Hebei Medical University&Hebei Institute of Mental Health&Hebei Clinical Research Center for Mental Disorders&Hebei Technology Innovation Center for Mental and Psychological Health Assessment and Intervention,Shijiazhuang 050031,China)

机构地区：[1]河北医科大学第一医院精神卫生中心、河北省精神卫生研究所、河北省精神心理疾病临床医学研究中心、河北省精神心理健康评估与干预技术创新中心,石家庄050031

出　　处：《神经疾病与精神卫生》2024年第9期659-664,共6页Journal of Neuroscience and Mental Health

基　　金：河北省省级科技计划资助(21377711D);河北省创新能力提升计划(199776245D);河北省引进国外智力项目(YZ202306)。

摘　　要：童年期创伤与静息态血压及心率存在着一定的关联性,是预测心血管疾病的重要风险因素。本文通过总结童年期创伤与静息态血压、心率和心血管疾病之间的相关性以及童年期创伤影响静息态血压、心率及心血管疾病的潜在机制,包括表观遗传学、神经内分泌、氧化应激、炎性反应、不良生活方式、心理应激等,明确童年期创伤对心血管系统的潜在影响,旨在为早期防治心血管疾病提供理论依据。Childhood trauma has a certain correlation with resting blood pressure and resting heart rate,which is an important risk factor for predicting cardiovascular disease.This review summarizes the correlation between childhood trauma and resting blood pressure and resting heart rate and cardiovascular disease,as well as the potential mechanisms of childhood trauma affecting resting blood pressure,resting heart rate and cardiovascular disease,including epigenetics,neuroendocrine,oxidative stress,inflammation,adverse lifestyle,psychological stress etc.The aim is to clarify the potential impact of childhood trauma on the cardiovascular system,and provide a theoretical basis for the prevention and treatment of cardiovascular disease.

关 键 词：心血管疾病 童年期创伤 静息态血压 静息心率 心率变异性 综述 

分 类 号：R54[医药卫生—心血管疾病]