猪急性腹泻综合征冠状病毒的流行、致病机制及防控研究进展  

Research progress on prevalence,pathogenesis and prevention and control of porcine acute diarrhea syndrome coronavirus

作　　者：陈梦茹 王悦 冯华朋 全滟平[1] 陈健[1] 舒建洪[1,2] 何玉龙 CHEN Mengru;WANG Yue;FENG Huapeng;QUAN Yanping;CHEN Jian;SHU Jianhong;HE Yulong(School of Life Sciences and Medicine,Zhejiang Sci-Tech University,Hangzhou,Zhejiang 310000,China;Zhejiang Hongsheng Biotechnology Co.,Ltd,Shaoxing,Zhejiang 312090,China)

机构地区：[1]浙江理工大学生命科学与医药学院,浙江杭州310000 [2]浙江洪晟生物科技股份有限公司,浙江绍兴312090

出　　处：《西北农林科技大学学报（自然科学版）》2024年第10期26-34,共9页Journal of Northwest A&F University(Natural Science Edition)

基　　金：浙江省“三农九方”农业科技协作计划“揭榜挂帅”项目(2022SNJF060);浙江省“领雁”研发攻关计划项目(2023C02023,2023C02047)。

摘　　要：目前发现的猪肠道冠状病毒主要有猪流行性腹泻病毒(PEDV)、猪三角冠状病毒(PDCoV)、猪传染性胃肠炎病毒(TGEV)和猪急性腹泻综合征冠状病毒(SADS-CoV)4种。其中SADS-CoV是2017年首次在我国广东省发现的一种猪肠道冠状病毒,该病毒感染后可致小于5日龄仔猪出现严重急性腹泻、急性呕吐、脱水等症状,死亡率较高,给养猪业造成巨大的经济损失。目前还未见针对SADS-CoV的有效药物和疫苗产品上市,从病毒传播、致病机制、诊断及预防控制等方面综述SADS-CoV的研究进展,期望为SADS-CoV的防控提供参考。The main porcine enteric coronaviruses currently discovered include porcine epidemic diarr-hea virus(PEDV),porcine deltacoronavirus(PDCoV),porcine transmissible gastroenteritis virus(TGEV)and swine acute diarrhea syndrome coronavirus(SADS-CoV).SADS-CoV is a porcine enteric coronavirus firstly discovered in Guangdong,China in 2017.Infection with the virus causes piglets less than 5 days old to develop symptoms such as severe acute diarrhea,acute vomiting,dehydration and high mortality,which causes huge economic losses to the pig industry.Currently,there are no effective drugs or vaccines against SADS-CoV on market.This article reviews the research progress of SADS-CoV from the aspects of virus transmission,pathogenesis,diagnosis,prevention and control,aiming to provide reference for the prevention and control of SADS-CoV.

关 键 词：猪急性腹泻综合征 冠状病毒 致病机制 病毒流行 病毒防控 

分 类 号：S852.651[农业科学—基础兽医学]