雌性生殖功能重构的研究进展  

The Research Progress on Female Fertility Regeneration

作　　者：黎婷 张院生 刘家旋 虞娜 LI Ting;ZHANG Yuansheng;LIU Jiaxuan;YU Na(Wuhu Institute of Technology,Wuhu,Anhui 241000;Detection of Food-borne Pathogenic Microorganisms Engineering Research Center of Wuhu,Wuhu,Anhui 241000;Wuhu Institute of Technology,Life and Health Engineering Research Center of Wuhu,Wuhu,Anhui 241000;Hefei Shushan District Lepet Animal Hospital,Hefei,Anhui 230000)

机构地区：[1]芜湖职业技术学院,安徽芜湖241000 [2]芜湖市食源性病原微生物检测工程技术研究中心,安徽芜湖241000 [3]芜湖职业技术学院芜湖市生命健康工程技术研究中心,安徽芜湖241000 [4]合肥市蜀山区乐宠动物医院,安徽合肥230000

出　　处：《呼伦贝尔学院学报》2024年第4期86-92,共7页Journal of Hulunbuir University

基　　金：2021年安徽省自然科学研究重点项目“bFGF调控GCs在卵巢去细胞生物支架中的增殖及机制研究”(KJ2021A1336);2018年芜湖职业技术学院校级人才项目“GCs在血管化卵巢去细胞生物支架中的增殖及功能鉴定”(wzyrc201801)。

摘　　要：辅助生殖技术(Assisted Reproductive Technology,ART)的发展解决了部分家庭不孕不育的问题。但是由于缺乏优质的生殖细胞,尤其是卵子,导致一些家庭实施辅助生殖技术失败。通过雌性生殖干细胞(female germline stem cells,FGSCs)或卵原干细胞(oogonial stem cells,OSCs)培养获得新卵子,在体外制备卵巢组织或直接进行体内应用,成为重构雌性生殖功能的新思路。The development of assisted reproductive technology,the dilemma of some infertility families has been solved.However,due to the lack of high-quality germ cells,especially the problem of eggs,some families have failed to implement assisted reproductive technology.New eggs are obtained by culture of female germline stem cells(FGSCs)or oogonial stem cells(OSCs),and ovarian tissue is prepared in vitro or directly applied in vivo,which has become a new idea for reconstituting female reproductive function.

关 键 词：雌性 生殖功能 重构 

分 类 号：S814.1[农业科学—畜牧学]