中药治疗便秘古今用药对比研究  

Comparative study on ancient and modern medicines for treating constipation

作　　者：陈汝玲 黄兴文 辛振杰 陈宗武 禤昭银 CHEN Ruling;HUANG Xingwen;XIN Zhenjie;CHEN Zongwu;XUAN Zhaoyin(Luoding Hospital of Traditional Chinese Medicine,Luoding 527200,China;Guangdong Yunfu Vocational College of Chinese Medicine,Xinxing 527400,China)

机构地区：[1]罗定市中医院,广东罗定527200 [2]广东云浮中医药职业学院,广东新兴527400

出　　处：《贵州科学》2024年第5期19-23,共5页Guizhou Science

基　　金：云浮市中药名师工作室建设项目(云中医函〔2022〕23号)。

摘　　要：目的:通过比较治疗便秘的古代复方和现代中成药用药的差异,探究古今治疗便秘的有效优选药物,并为该类中成药的研发提供科学参考。方法:通过建立治疗便秘的中药方剂数据库,采用SPSS 22.0统计软件对古今通便用药进行比较,对常用药物进行整理和分析。结果:古代复方以大黄、甘草、当归、火麻仁较为常用;现代中成药以大黄、甘草、黄芩、黄连较为常用。古今用药存在显著性差异(P<0.05)。结论:通过对古今治疗便秘的用药规律对比研究,可发现治疗便秘的优选药物和药对,并为今后中医临床治疗便秘和中成药研制提供科学参考。In this study we compared the differences between ancient and modern Chinese medicines for treating constipation,and explored the effective drugs for treating constipation in ancient and modern times,so as to provide scientific reference for the development of such Chinese patent medicines.After establishing a database of traditional Chinese medicine prescriptions for treating constipation,SPSS 22.0 statistical software was used to compare the ancient and modern laxative medications,and the common drugs were sorted and analyzed.In ancient times,rhubarb,licorice,angelica and hemp were more commonly used;in modern times,rhubarb,licorice,astragalus and berberine were more commonly used.There was a significant difference between ancient and modern medications(P<0.05).Through the comparative study of ancient and modern medication rules of constipation,this study has found the preferred drugs and drug pairs for the treatment of constipation,and has provided scientific reference for future clinical treatment of constipation and the development of Chinese patent medicines.

关 键 词：古代复方 中成药 便秘 用药规律 

分 类 号：R256.35[医药卫生—中医内科学]