Fiber Optic SPR POCT: A Novel Nucleic Acid Detection Biosensor for Environmental Viruses  

作　　者：Jing Wang Zhaojun Duan Dixian Luo 

机构地区：[1]Department of Laboratory Medicine,Shenzhen Hospital of Integrated Traditional and Western Medicine,Shenzhen,China [2]National Institute for Viral Disease Control and Prevention,China Center for Disease Control and Prevention,Beijing,China.

出　　处：《Research》2024年第3期791-793,共3页研究（英文）

摘　　要：In the post-COVID-19 pandemic era, the long-term surveillance of pathogens is still important. The rapid detection of pathogens facilitates the accurate and convenient real-time monitoring of microbial contamination and improves the management of diseases. Here, a novel surface plasmon resonance (SPR)-based point of care testing (POCT) approach of microorganism nucleic acids with the guidance of CRISPR enzyme is described, including the application of optical fiber-based detection of trace SARS-CoV2 virus in sewage water on SPR and validation of the plasmonic biosensor for the detection of single-nucleotide mutations in natural water samples.

关 键 词：POCT SPR CONVENIENT 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]