通调针刺法联合康复疗法治疗气虚血瘀型脑梗死后运动障碍临床观察  

Clinical Effect of Regulating Acupuncture Combined with Rehabilitation Therapy in Treatment of Dyskinesia with Qi Deficiency and Blood Stasis after Cerebral Infarction

作　　者：张玲[1] 张国庆[1] 陈赟[1] 朱玲玲[1] 张君宇[1] 童婷婷 汪俊丽 柳刚[1] 张闻东[1] ZHANG Ling;ZHANG Guoqing;CHEN Yun;ZHU Lingling;ZHANG Junyu;TONG Tingting;WANG Junli;LIU Gang;ZHANG Wendong(The Second Affiliated Hospital of Anhui University of Chinese Medicine,Anhui Hefei 230061,China)

机构地区：[1]安徽中医药大学第二附属医院,安徽合肥230061

出　　处：《安徽中医药大学学报》2024年第5期39-44,共6页Journal of Anhui University of Chinese Medicine

基　　金：安徽省重点研究与开发计划(2022e07020026);安徽省第十三批115产业创新团队项目(皖人才办〔2020〕4号);安徽中医药大学第二附属医院人才支持计划(杏林计划)(院发〔2023〕118号)。

摘　　要：目的评估通调针刺法联合康复疗法治疗气虚血瘀型脑梗死后运动障碍的临床疗效。方法将60例气虚血瘀型脑梗死后运动障碍患者随机分为对照组和治疗组,每组30例。两组患者均给予基础治疗,对照组患者给予康复治疗,治疗组患者给予康复治疗联合通调针刺法治疗,两组疗程均为4周。比较治疗前后两组患者简化Fugl-Meyer评估(Fugl-Meyer assessment,FMA)量表评分和日常生活活动能力(activity of daily living,ADL)量表评分、气虚血瘀证证候积分、血清转铁蛋白(transferrin,TF)和神经生长因子(nerve growth factor,NGF)水平,对比两组总体疗效。结果治疗组脱落2例患者,对照组脱落1例患者。与治疗前比较,两组患者治疗后FMA量表评分和ADL量表评分均显著上升(P<0.05),气虚血瘀证证候积分显著降低(P<0.05),血清TF和NGF水平显著升高(P<0.05),且治疗组FMA量表评分和ADL量表评分及血清TF和NGF水平升高程度、气虚血瘀证证候积分降低程度均显著大于对照组(P<0.05)。治疗组临床疗效显著优于对照组(P<0.05)。结论通调针刺法联合康复疗法治疗气虚血瘀型脑梗死后运动障碍疗效显著。Objective To investigate the clinical effect of regulating acupuncture combined with rehabilitation therapy in the treatment of dyskinesia with Qi deficiency and blood stasis after cerebral infarction.Methods A total of 60 patients with dyskinesia with Qi deficiency and blood stasis after cerebral infarction were randomly divided into treatment group and control group,with 30 patients in each group.In addition to basic treatment,the patients in the control group were given rehabilitation therapy,and those in the treatment group were given rehabilitation therapy and regulating acupuncture.The two groups were observed in terms of Fugl-Meyer Assessment(FMA)score,Activities of Daily Living(ADL)score,Qi deficiency and blood stasis syndrome score,serum transferrin(TF),and nerve growth factor(NGF)before treatment and after 4 weeks of treatment,and overall treatment outcome was compared between the two groups.Results Two patients in the treatment group and one patient in the control group were lost to follow-up.After treatment,both groups had significant increases in FMA and ADL scores(P<0.05),a significant reduction in the syndrome score of Qi deficiency and blood stasis(P<0.05),and significant increases in the serum levels of TF and NGF(P<0.05),and compared with the control group,the treatment group had significantly greater increases in FMA and ADL scores and the serum levels of TF and NGF,as well as a significantly greater reduction in the syndrome score of Qi deficiency and blood stasis(P<0.05).The treatment group had a significantly better clinical outcome than the control group(P<0.05).Conclusion Regulating acupuncture combined with rehabilitation therapy has a marked clinical effect in the treatment of dyskinesia with Qi deficiency and blood stasis after cerebral infarction.

关 键 词：脑梗死后运动障碍 气虚血瘀证 通调针刺 转铁蛋白 神经生长因子 

分 类 号：R246.6[医药卫生—针灸推拿学]